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ε-globin expression is regulated by SUV4-20h1.
Wang Y, Rank G, Li Z, Wang Y, Ju J, Nuber A, Wu Y, Liu M, Nie M, Huang F, Cerruti L, Ma C, Tan R, Schotta G, Jane SM, Zeng CK, Zhao Q. Wang Y, et al. Among authors: schotta g. Haematologica. 2016 May;101(5):e168-72. doi: 10.3324/haematol.2015.139980. Epub 2016 Jan 22. Haematologica. 2016. PMID: 26802048 Free PMC article. No abstract available.
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
Bromberg KD, Mitchell TR, Upadhyay AK, Jakob CG, Jhala MA, Comess KM, Lasko LM, Li C, Tuzon CT, Dai Y, Li F, Eram MS, Nuber A, Soni NB, Manaves V, Algire MA, Sweis RF, Torrent M, Schotta G, Sun C, Michaelides MR, Shoemaker AR, Arrowsmith CH, Brown PJ, Santhakumar V, Martin A, Rice JC, Chiang GG, Vedadi M, Barsyte-Lovejoy D, Pappano WN. Bromberg KD, et al. Among authors: schotta g. Nat Chem Biol. 2017 Mar;13(3):317-324. doi: 10.1038/nchembio.2282. Epub 2017 Jan 23. Nat Chem Biol. 2017. PMID: 28114273
CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.
Dambacher S, Deng W, Hahn M, Sadic D, Fröhlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G. Dambacher S, et al. Among authors: schotta g. Nucleus. 2012 Jan-Feb;3(1):101-10. doi: 10.4161/nucl.18955. Nucleus. 2012. PMID: 22540025 Free PMC article.
SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation.
Južnić L, Peuker K, Strigli A, Brosch M, Herrmann A, Häsler R, Koch M, Matthiesen L, Zeissig Y, Löscher BS, Nuber A, Schotta G, Neumeister V, Chavakis T, Kurth T, Lesche M, Dahl A, von Mässenhausen A, Linkermann A, Schreiber S, Aden K, Rosenstiel PC, Franke A, Hampe J, Zeissig S. Južnić L, et al. Among authors: schotta g. Gut. 2021 Mar;70(3):485-498. doi: 10.1136/gutjnl-2020-321339. Epub 2020 Jun 5. Gut. 2021. PMID: 32503845 Free PMC article.
Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin.
Hahn M, Dambacher S, Dulev S, Kuznetsova AY, Eck S, Wörz S, Sadic D, Schulte M, Mallm JP, Maiser A, Debs P, von Melchner H, Leonhardt H, Schermelleh L, Rohr K, Rippe K, Storchova Z, Schotta G. Hahn M, et al. Among authors: schotta g. Genes Dev. 2013 Apr 15;27(8):859-72. doi: 10.1101/gad.210377.112. Epub 2013 Apr 18. Genes Dev. 2013. PMID: 23599346 Free PMC article.
Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm.
Wang Z, Fan R, Russo A, Cernilogar FM, Nuber A, Schirge S, Shcherbakova I, Dzhilyanova I, Ugur E, Anton T, Richter L, Leonhardt H, Lickert H, Schotta G. Wang Z, et al. Among authors: schotta g. Nat Commun. 2022 Sep 19;13(1):5447. doi: 10.1038/s41467-022-32978-7. Nat Commun. 2022. PMID: 36123357 Free PMC article.
The compact view on heterochromatin.
Dambacher S, Hahn M, Schotta G. Dambacher S, et al. Among authors: schotta g. Cell Cycle. 2013 Sep 15;12(18):2925-6. doi: 10.4161/cc.26179. Epub 2013 Aug 23. Cell Cycle. 2013. PMID: 23974091 Free PMC article. No abstract available.
85 results