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Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer.
Talati PG, Gu L, Ellsworth EM, Girondo MA, Trerotola M, Hoang DT, Leiby B, Dagvadorj A, McCue PA, Lallas CD, Trabulsi EJ, Gomella L, Aplin AE, Languino L, Fatatis A, Rui H, Nevalainen MT. Talati PG, et al. Among authors: nevalainen mt. Am J Pathol. 2015 Sep;185(9):2505-22. doi: 10.1016/j.ajpath.2015.04.026. Am J Pathol. 2015. PMID: 26362718 Free PMC article.
Enzalutamide-Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant Prostate Cancer Growth Providing an Exploitable Molecular Target for Jak2 Inhibitors.
Udhane V, Maranto C, Hoang DT, Gu L, Erickson A, Devi S, Talati PG, Banerjee A, Iczkowski KA, Jacobsohn K, See WA, Mirtti T, Kilari D, Nevalainen MT. Udhane V, et al. Among authors: nevalainen mt. Mol Cancer Ther. 2020 Jan;19(1):231-246. doi: 10.1158/1535-7163.MCT-19-0508. Epub 2019 Sep 23. Mol Cancer Ther. 2020. PMID: 31548294 Free PMC article.
Stat5 induces androgen receptor (AR) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling.
Maranto C, Sabharwal L, Udhane V, Pitzen SP, McCluskey B, Qi S, O'Connor C, Devi S, Johnson S, Jacobsohn K, Banerjee A, Iczkowski KA, Wang L, Dehm SM, Nevalainen MT. Maranto C, et al. Among authors: nevalainen mt. Sci Adv. 2024 Mar;10(9):eadi2742. doi: 10.1126/sciadv.adi2742. Epub 2024 Feb 28. Sci Adv. 2024. PMID: 38416822 Free PMC article.
95 results