Zanger UM - Search Results

1

Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma.

Pellé L, Cipollini M, Tremmel R, Romei C, Figlioli G, Gemignani F, Melaiu O, De Santi C, Barone E, Elisei R, Seiser E, Innocenti F, Zanger UM, Landi S. Pellé L, et al. Among authors: zanger um. Arch Toxicol. 2016 Dec;90(12):3099-3109. doi: 10.1007/s00204-016-1660-8. Epub 2016 Jan 19. Arch Toxicol. 2016. PMID: 26783003

2

Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels.

Tremmel R, Herrmann K, Engst W, Meinl W, Klein K, Glatt H, Zanger UM. Tremmel R, et al. Among authors: zanger um. Arch Toxicol. 2017 Oct;91(10):3329-3339. doi: 10.1007/s00204-017-1955-4. Epub 2017 Mar 22. Arch Toxicol. 2017. PMID: 28326452

3

Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1.

Tremmel R, Klein K, Winter S, Schaeffeler E, Zanger UM. Tremmel R, et al. Among authors: zanger um. Pharmacogenomics J. 2016 Nov;16(6):551-558. doi: 10.1038/tpj.2015.69. Epub 2015 Oct 27. Pharmacogenomics J. 2016. PMID: 26503817

4

Genetics, epigenetics, and regulation of drug-metabolizing cytochrome p450 enzymes.

Zanger UM, Klein K, Thomas M, Rieger JK, Tremmel R, Kandel BA, Klein M, Magdy T. Zanger UM, et al. Clin Pharmacol Ther. 2014 Mar;95(3):258-61. doi: 10.1038/clpt.2013.220. Epub 2013 Nov 6. Clin Pharmacol Ther. 2014. PMID: 24196843 Review. No abstract available.

5

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort.

Klein K, Tremmel R, Winter S, Fehr S, Battke F, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM. Klein K, et al. Among authors: zanger um. Front Genet. 2019 Jan 31;10:7. doi: 10.3389/fgene.2019.00007. eCollection 2019. Front Genet. 2019. PMID: 30766545 Free PMC article.

6

Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression.

Tremmel R, Klein K, Battke F, Fehr S, Winter S, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM. Tremmel R, et al. Among authors: zanger um. Hum Genet. 2020 Feb;139(2):137-149. doi: 10.1007/s00439-019-02093-7. Epub 2019 Nov 30. Hum Genet. 2020. PMID: 31786673

7

The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes.

Johänning J, Kröner P, Thomas M, Zanger UM, Nörenberg A, Eichelbaum M, Schwab M, Brauch H, Schroth W, Mürdter TE. Johänning J, et al. Among authors: zanger um. Arch Toxicol. 2018 Mar;92(3):1099-1112. doi: 10.1007/s00204-017-2147-y. Epub 2017 Dec 28. Arch Toxicol. 2018. PMID: 29285606 Free PMC article.

8

Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms.

Bitter A, Rümmele P, Klein K, Kandel BA, Rieger JK, Nüssler AK, Zanger UM, Trauner M, Schwab M, Burk O. Bitter A, et al. Among authors: zanger um. Arch Toxicol. 2015 Nov;89(11):2089-103. doi: 10.1007/s00204-014-1348-x. Epub 2014 Sep 3. Arch Toxicol. 2015. PMID: 25182422

9

Expression variability of absorption, distribution, metabolism, excretion-related microRNAs in human liver: influence of nongenetic factors and association with gene expression.

Rieger JK, Klein K, Winter S, Zanger UM. Rieger JK, et al. Among authors: zanger um. Drug Metab Dispos. 2013 Oct;41(10):1752-62. doi: 10.1124/dmd.113.052126. Epub 2013 Jun 3. Drug Metab Dispos. 2013. PMID: 23733276

10

Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism.

Crane AL, Klein K, Zanger UM, Olson JR. Crane AL, et al. Among authors: zanger um. Toxicology. 2012 Mar 11;293(1-3):115-122. doi: 10.1016/j.tox.2012.01.006. Epub 2012 Jan 18. Toxicology. 2012. PMID: 22281205 Free PMC article.

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