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Inflammation and oxidative stress caused by nitric oxide synthase uncoupling might lead to left ventricular diastolic and systolic dysfunction in patients with hypertension.
Szelényi Z, Fazakas Á, Szénási G, Kiss M, Tegze N, Fekete BC, Nagy E, Bodó I, Nagy B, Molvarec A, Patócs A, Pepó L, Prohászka Z, Vereckei A. Szelényi Z, et al. Among authors: fazakas a. J Geriatr Cardiol. 2015 Jan;12(1):1-10. doi: 10.11909/j.issn.1671-5411.2015.01.001. J Geriatr Cardiol. 2015. PMID: 25678898 Free PMC article.
The HLA 8.1 ancestral haplotype is strongly linked to the C allele of -429T>C promoter polymorphism of receptor of the advanced glycation endproduct (RAGE) gene. Haplotype-independent association of the -429C allele with high hemoglobinA1C levels in diabetic patients.
Laki J, Kiszel P, Vatay A, Blaskó B, Kovács M, Körner A, Madácsy L, Blatniczky L, Almássy Z, Szalai C, Rajczy K, Pozsonyi E, Karádi I, Fazakas A, Hosszúfalusi N, Pánczél P, Arason GJ, Wu YL, Zhou B, Yang Y, Yu CY, Füst G. Laki J, et al. Among authors: fazakas a. Mol Immunol. 2007 Jan;44(4):648-55. doi: 10.1016/j.molimm.2006.01.011. Epub 2006 Feb 28. Mol Immunol. 2007. PMID: 16504296
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