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Treatment with the apoptosis inhibitor Asunercept reduces clone sizes in patients with lower risk Myelodysplastic Neoplasms.
Streuer A, Jann JC, Boch T, Mossner M, Riabov V, Schmitt N, Altrock E, Xu Q, Demmerle M, Nowak V, Oblaender J, Palme I, Weimer N, Rapp F, Metzgeroth G, Hecht A, Höger T, Merz C, Hofmann WK, Nolte F, Nowak D. Streuer A, et al. Among authors: jann jc. Ann Hematol. 2024 Apr;103(4):1221-1233. doi: 10.1007/s00277-024-05664-5. Epub 2024 Feb 27. Ann Hematol. 2024. PMID: 38413410 Free PMC article.
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML.
Wheeler EC, Martin BJE, Doyle WC, Neaher S, Conway CA, Pitton CN, Gorelov RA, Donahue M, Jann JC, Abdel-Wahab O, Taylor J, Seiler M, Buonamici S, Pikman Y, Garcia JS, Belizaire R, Adelman K, Tothova Z. Wheeler EC, et al. Among authors: jann jc. Sci Transl Med. 2024 Jan 3;16(728):eade2774. doi: 10.1126/scitranslmed.ade2774. Epub 2024 Jan 3. Sci Transl Med. 2024. PMID: 38170787
ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms.
Riabov V, Xu Q, Schmitt N, Streuer A, Ge G, Bolanos L, Wunderlich M, Jann JC, Wein A, Altrock E, Demmerle M, Mukherjee S, Ali AM, Rapp F, Nowak V, Weimer N, Obländer J, Palme I, Göl M, Jawhar A, Darwich A, Wuchter P, Weiss C, Raza A, Foulks JM, Starczynowski DT, Yang FC, Metzgeroth G, Steiner L, Jawhar M, Hofmann WK, Nowak D. Riabov V, et al. Among authors: jann jc. Haematologica. 2024 May 1;109(5):1426-1438. doi: 10.3324/haematol.2023.282921. Haematologica. 2024. PMID: 37916386 Free PMC article.
Significant improvement of bone marrow-derived MSC expansion from MDS patients by defined xeno-free medium.
Altrock E, Sens-Albert C, Hofmann F, Riabov V, Schmitt N, Xu Q, Jann JC, Rapp F, Steiner L, Streuer A, Nowak V, Obländer J, Weimer N, Palme I, Göl M, Darwich A, Wuchter P, Metzgeroth G, Jawhar M, Hofmann WK, Nowak D. Altrock E, et al. Among authors: jann jc. Stem Cell Res Ther. 2023 Jun 7;14(1):156. doi: 10.1186/s13287-023-03386-5. Stem Cell Res Ther. 2023. PMID: 37287056 Free PMC article.
A Review of Serious Gaming as an Intervention for HIV Prevention.
Smith AU, Khawly GM, Jann J, Zetina APM, Padilla J, Schnall R. Smith AU, et al. Among authors: jann j. Curr HIV/AIDS Rep. 2023 Aug;20(4):181-205. doi: 10.1007/s11904-023-00659-9. Epub 2023 May 22. Curr HIV/AIDS Rep. 2023. PMID: 37213045 Review.
Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies.
Xu Q, Streuer A, Jann JC, Altrock E, Schmitt N, Flach J, Sens-Albert C, Rapp F, Wolf J, Nowak V, Weimer N, Obländer J, Palme I, Kuzina M, Jawhar A, Darwich A, Weis CA, Marx A, Wuchter P, Costina V, Jäger E, Sperk E, Neumaier M, Fabarius A, Metzgeroth G, Nolte F, Steiner L, Levkin PA, Jawhar M, Hofmann WK, Riabov V, Nowak D. Xu Q, et al. Among authors: jann jc. Nat Commun. 2023 Mar 17;14(1):1497. doi: 10.1038/s41467-023-37175-8. Nat Commun. 2023. PMID: 36932114 Free PMC article.
48 results