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Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).
Bioorg Med Chem. 2016 Feb 15;24(4):521-44. doi: 10.1016/j.bmc.2015.11.045. Epub 2015 Dec 1.
Bioorg Med Chem. 2016.
PMID: 26762835
Free PMC article.
Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblastic leukemia.
Padgaonkar A, Rechkoblit O, Vasquez-Del Carpio R, Pallela V, Venkata Subbaiah D, Cosenza SC, Baker SJ, Ramana Reddy MV, Aggarwal A, Reddy EP.
Padgaonkar A, et al.
Oncotarget. 2018 Dec 28;9(102):37753-37765. doi: 10.18632/oncotarget.26514. eCollection 2018 Dec 28.
Oncotarget. 2018.
PMID: 30701029
Free PMC article.
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Synthesis and bioassay of amino-pyrazolone, amino-isoxazolone and amino-pyrimidinone derivatives.
Padmavathi V, Venkata Subbaiah DR, Mahesh K, Radha Lakshmi T.
Padmavathi V, et al. Among authors: venkata subbaiah dr.
Chem Pharm Bull (Tokyo). 2007 Dec;55(12):1704-9. doi: 10.1248/cpb.55.1704.
Chem Pharm Bull (Tokyo). 2007.
PMID: 18057743
Free article.
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Biological evaluation of sulfone derivatives as anti-inflammatory and tumor cells growth inhibitory agents.
Fang SH, Padmavathi V, Rao YK, Venkata Subbaiah DR, Thriveni P, Geethangili M, Padmaja A, Tzeng YM.
Fang SH, et al. Among authors: venkata subbaiah dr.
Int Immunopharmacol. 2006 Nov;6(11):1699-705. doi: 10.1016/j.intimp.2006.07.004. Epub 2006 Jul 31.
Int Immunopharmacol. 2006.
PMID: 16979124
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