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Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).
Reddy MV, Akula B, Jatiani S, Vasquez-Del Carpio R, Billa VK, Mallireddigari MR, Cosenza SC, Venkata Subbaiah DR, Bharathi EV, Pallela VR, Ramkumar P, Jain R, Aggarwal AK, Reddy EP. Reddy MV, et al. Among authors: jatiani s. Bioorg Med Chem. 2016 Feb 15;24(4):521-44. doi: 10.1016/j.bmc.2015.11.045. Epub 2015 Dec 1. Bioorg Med Chem. 2016. PMID: 26762835 Free PMC article.
SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma.
Jatiani SS, Christie S, Leshchenko VV, Jain R, Kapoor A, Bisignano P, Lee C, Kaniskan HÜ, Edwards D, Meng F, Laganà A, Youssef Y, Wiestner A, Alinari L, Jin J, Filizola M, Aggarwal AK, Parekh S. Jatiani SS, et al. Clin Cancer Res. 2021 Aug 15;27(16):4652-4663. doi: 10.1158/1078-0432.CCR-20-5039. Epub 2021 Jun 22. Clin Cancer Res. 2021. PMID: 34158358 Free PMC article.
SOX11 augments BCR signaling to drive MCL-like tumor development.
Kuo PY, Jatiani SS, Rahman AH, Edwards D, Jiang Z, Ahr K, Perumal D, Leshchenko VV, Brody J, Shaknovich R, Ye BH, Parekh S. Kuo PY, et al. Among authors: jatiani ss. Blood. 2018 May 17;131(20):2247-2255. doi: 10.1182/blood-2018-02-832535. Epub 2018 Apr 3. Blood. 2018. PMID: 29615403 Free PMC article.
Myeloma CAR-T CRS Management With IL-1R Antagonist Anakinra.
Jatiani SS, Aleman A, Madduri D, Chari A, Cho HJ, Richard S, Richter J, Brody J, Jagannath S, Parekh S. Jatiani SS, et al. Clin Lymphoma Myeloma Leuk. 2020 Sep;20(9):632-636.e1. doi: 10.1016/j.clml.2020.04.020. Epub 2020 May 11. Clin Lymphoma Myeloma Leuk. 2020. PMID: 32553791 Free PMC article. No abstract available.
Dynamin interacts with members of the sumoylation machinery.
Mishra RK, Jatiani SS, Kumar A, Simhadri VR, Hosur RV, Mittal R. Mishra RK, et al. Among authors: jatiani ss. J Biol Chem. 2004 Jul 23;279(30):31445-54. doi: 10.1074/jbc.M402911200. Epub 2004 Apr 30. J Biol Chem. 2004. PMID: 15123615 Free article.
11 results