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FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich MF, Lim R, Zimmermann B, Aspalter IM, Franco CA, Boettger T, Braun T, Fruttiger M, Rajewsky K, Keller C, Brüning JC, Gerhardt H, Carmeliet P, Potente M. Wilhelm K, et al. Among authors: fruttiger m. Nature. 2016 Jan 14;529(7585):216-20. doi: 10.1038/nature16498. Epub 2016 Jan 6. Nature. 2016. PMID: 26735015 Free PMC article.
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Tammela T, Zarkada G, Nurmi H, Jakobsson L, Heinolainen K, Tvorogov D, Zheng W, Franco CA, Murtomäki A, Aranda E, Miura N, Ylä-Herttuala S, Fruttiger M, Mäkinen T, Eichmann A, Pollard JW, Gerhardt H, Alitalo K. Tammela T, et al. Among authors: fruttiger m. Nat Cell Biol. 2011 Sep 11;13(10):1202-13. doi: 10.1038/ncb2331. Nat Cell Biol. 2011. PMID: 21909098 Free PMC article.
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Aspalter IM, Gordon E, Dubrac A, Ragab A, Narloch J, Vizán P, Geudens I, Collins RT, Franco CA, Abrahams CL, Thurston G, Fruttiger M, Rosewell I, Eichmann A, Gerhardt H. Aspalter IM, et al. Among authors: fruttiger m. Nat Commun. 2015 Jun 17;6:7264. doi: 10.1038/ncomms8264. Nat Commun. 2015. PMID: 26081042 Free PMC article.
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, Pandolfi PP, Bigas A, Carracedo A, Gerhardt H, Graupera M. Serra H, et al. Among authors: fruttiger m. Nat Commun. 2015 Jul 31;6:7935. doi: 10.1038/ncomms8935. Nat Commun. 2015. PMID: 26228240 Free PMC article.
Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, Ivanov A, Szymborska A, Patone G, Kunz S, Sommermeyer D, Engels B, Leisegang M, Textor A, Fehling HJ, Fruttiger M, Lohoff M, Herrmann A, Yu H, Weichselbaum R, Uckert W, Hübner N, Gerhardt H, Beule D, Schreiber H, Blankenstein T. Kammertoens T, et al. Among authors: fruttiger m. Nature. 2017 May 4;545(7652):98-102. doi: 10.1038/nature22311. Epub 2017 Apr 26. Nature. 2017. PMID: 28445461 Free PMC article.
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms.
Stalmans I, Ng YS, Rohan R, Fruttiger M, Bouché A, Yuce A, Fujisawa H, Hermans B, Shani M, Jansen S, Hicklin D, Anderson DJ, Gardiner T, Hammes HP, Moons L, Dewerchin M, Collen D, Carmeliet P, D'Amore PA. Stalmans I, et al. Among authors: fruttiger m. J Clin Invest. 2002 Feb;109(3):327-36. doi: 10.1172/JCI14362. J Clin Invest. 2002. PMID: 11827992 Free PMC article.
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.
Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, Jeltsch M, Mitchell C, Alitalo K, Shima D, Betsholtz C. Gerhardt H, et al. Among authors: fruttiger m. J Cell Biol. 2003 Jun 23;161(6):1163-77. doi: 10.1083/jcb.200302047. Epub 2003 Jun 16. J Cell Biol. 2003. PMID: 12810700 Free PMC article.
139 results