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Page 1
A Cell Biologist's Field Guide to Aurora Kinase Inhibitors.
de Groot CO, Hsia JE, Anzola JV, Motamedi A, Yoon M, Wong YL, Jenkins D, Lee HJ, Martinez MB, Davis RL, Gahman TC, Desai A, Shiau AK. de Groot CO, et al. Among authors: shiau ak. Front Oncol. 2015 Dec 21;5:285. doi: 10.3389/fonc.2015.00285. eCollection 2015. Front Oncol. 2015. PMID: 26732741 Free PMC article.
Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors.
Pinkerton AB, Lee TT, Hoffman TZ, Wang Y, Kahraman M, Cook TG, Severance D, Gahman TC, Noble SA, Shiau AK, Davis RL. Pinkerton AB, et al. Among authors: shiau ak. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3562-9. doi: 10.1016/j.bmcl.2007.04.076. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17498954
KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo.
Hassig CA, Symons KT, Guo X, Nguyen PM, Annable T, Wash PL, Payne JE, Jenkins DA, Bonnefous C, Trotter C, Wang Y, Anzola JV, Milkova EL, Hoffman TZ, Dozier SJ, Wiley BM, Saven A, Malecha JW, Davis RL, Muhammad J, Shiau AK, Noble SA, Rao TS, Smith ND, Hager JH. Hassig CA, et al. Among authors: shiau ak. Mol Cancer Ther. 2008 May;7(5):1054-65. doi: 10.1158/1535-7163.MCT-07-2347. Mol Cancer Ther. 2008. PMID: 18483295
Water-soluble PDE4 inhibitors for the treatment of dry eye.
Govek SP, Oshiro G, Anzola JV, Beauregard C, Chen J, Coyle AR, Gamache DA, Hellberg MR, Hsien JN, Lerch JM, Liao JC, Malecha JW, Staszewski LM, Thomas DJ, Yanni JM, Noble SA, Shiau AK. Govek SP, et al. Among authors: shiau ak. Bioorg Med Chem Lett. 2010 May 1;20(9):2928-32. doi: 10.1016/j.bmcl.2010.03.023. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20378348
Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
Davis RL, Kahraman M, Prins TJ, Beaver Y, Cook TG, Cramp J, Cayanan CS, Gardiner EM, McLaughlin MA, Clark AF, Hellberg MR, Shiau AK, Noble SA, Borchardt AJ. Davis RL, et al. Among authors: shiau ak. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3361-6. doi: 10.1016/j.bmcl.2010.04.020. Epub 2010 Apr 11. Bioorg Med Chem Lett. 2010. PMID: 20434334
Pharmacological characterization of KLYP961, a dual inhibitor of inducible and neuronal nitric-oxide synthases.
Symons KT, Nguyen PM, Massari ME, Anzola JV, Staszewski LM, Wang L, Yazdani N, Dorow S, Muhammad J, Sablad M, Rozenkrants N, Bonefous C, Payne JE, Rix PJ, Shiau AK, Noble SA, Smith ND, Hassig CA, Zhang Y, Rao TS. Symons KT, et al. Among authors: shiau ak. J Pharmacol Exp Ther. 2011 Feb;336(2):468-78. doi: 10.1124/jpet.110.172817. Epub 2010 Oct 29. J Pharmacol Exp Ther. 2011. PMID: 21036913
Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.
Wong YL, Anzola JV, Davis RL, Yoon M, Motamedi A, Kroll A, Seo CP, Hsia JE, Kim SK, Mitchell JW, Mitchell BJ, Desai A, Gahman TC, Shiau AK, Oegema K. Wong YL, et al. Among authors: shiau ak. Science. 2015 Jun 5;348(6239):1155-60. doi: 10.1126/science.aaa5111. Epub 2015 Apr 30. Science. 2015. PMID: 25931445 Free PMC article.
65 results