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Page 1
Benzimidazolone p38 inhibitors.
Dombroski MA, Letavic MA, McClure KF, Barberia JT, Carty TJ, Cortina SR, Csiki C, Dipesa AJ, Elliott NC, Gabel CA, Jordan CK, Labasi JM, Martin WH, Peese KM, Stock IA, Svensson L, Sweeney FJ, Yu CH. Dombroski MA, et al. Among authors: letavic ma. Bioorg Med Chem Lett. 2004 Feb 23;14(4):919-23. doi: 10.1016/j.bmcl.2003.12.023. Bioorg Med Chem Lett. 2004. PMID: 15012994
Recent medicinal chemistry of the histamine H3 receptor.
Letavic MA, Barbier AJ, Dvorak CA, Carruthers NI. Letavic MA, et al. Prog Med Chem. 2006;44:181-206. doi: 10.1016/S0079-6468(05)44405-7. Prog Med Chem. 2006. PMID: 16697898 Review. No abstract available.
Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore.
Keith JM, Gomez LA, Letavic MA, Ly KS, Jablonowski JA, Seierstad M, Barbier AJ, Wilson SJ, Boggs JD, Fraser IC, Mazur C, Lovenberg TW, Carruthers NI. Keith JM, et al. Among authors: letavic ma. Bioorg Med Chem Lett. 2007 Feb 1;17(3):702-6. doi: 10.1016/j.bmcl.2006.10.089. Epub 2006 Nov 2. Bioorg Med Chem Lett. 2007. PMID: 17107798
Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.
Letavic MA, Keith JM, Jablonowski JA, Stocking EM, Gomez LA, Ly KS, Miller JM, Barbier AJ, Bonaventure P, Boggs JD, Wilson SJ, Miller KL, Lord B, McAllister HM, Tognarelli DJ, Wu J, Abad MC, Schubert C, Lovenberg TW, Carruthers NI. Letavic MA, et al. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1047-51. doi: 10.1016/j.bmcl.2006.11.036. Epub 2006 Nov 16. Bioorg Med Chem Lett. 2007. PMID: 17127059
Histamine H3 receptor antagonists: from target identification to drug leads.
Bonaventure P, Letavic M, Dugovic C, Wilson S, Aluisio L, Pudiak C, Lord B, Mazur C, Kamme F, Nishino S, Carruthers N, Lovenberg T. Bonaventure P, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1084-96. doi: 10.1016/j.bcp.2006.10.031. Epub 2006 Nov 3. Biochem Pharmacol. 2007. PMID: 17129577
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Letavic MA, Stocking EM, Barbier AJ, Bonaventure P, Boggs JD, Lord B, Miller KL, Wilson SJ, Carruthers NI. Letavic MA, et al. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4799-803. doi: 10.1016/j.bmcl.2007.06.061. Epub 2007 Jun 26. Bioorg Med Chem Lett. 2007. PMID: 17616397
Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.
Barbier AJ, Aluisio L, Lord B, Qu Y, Wilson SJ, Boggs JD, Bonaventure P, Miller K, Fraser I, Dvorak L, Pudiak C, Dugovic C, Shelton J, Mazur C, Letavic MA, Carruthers NI, Lovenberg TW. Barbier AJ, et al. Among authors: letavic ma. Eur J Pharmacol. 2007 Dec 8;576(1-3):43-54. doi: 10.1016/j.ejphar.2007.08.009. Epub 2007 Aug 14. Eur J Pharmacol. 2007. PMID: 17765221
Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.
Ly KS, Letavic MA, Keith JM, Miller JM, Stocking EM, Barbier AJ, Bonaventure P, Lord B, Jiang X, Boggs JD, Dvorak L, Miller KL, Nepomuceno D, Wilson SJ, Carruthers NI. Ly KS, et al. Among authors: letavic ma. Bioorg Med Chem Lett. 2008 Jan 1;18(1):39-43. doi: 10.1016/j.bmcl.2007.11.016. Epub 2007 Nov 13. Bioorg Med Chem Lett. 2008. PMID: 18060777
63 results