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Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.
Vukovic M, Guitart AV, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J, Iglesias JM, Allen L, Glykofrydis F, Subramani C, Armesilla-Diaz A, Post AE, Schaak K, Gezer D, So CW, Holyoake TL, Wood A, O'Carroll D, Ratcliffe PJ, Kranc KR. Vukovic M, et al. J Exp Med. 2015 Dec 14;212(13):2223-34. doi: 10.1084/jem.20150452. Epub 2015 Dec 7. J Exp Med. 2015. PMID: 26642852 Free PMC article.
An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein.
Dewari PS, Southgate B, Mccarten K, Monogarov G, O'Duibhir E, Quinn N, Tyrer A, Leitner MC, Plumb C, Kalantzaki M, Blin C, Finch R, Bressan RB, Morrison G, Jacobi AM, Behlke MA, von Kriegsheim A, Tomlinson S, Krijgsveld J, Pollard SM. Dewari PS, et al. Among authors: o duibhir e. Elife. 2018 Apr 11;7:e35069. doi: 10.7554/eLife.35069. Elife. 2018. PMID: 29638216 Free PMC article.
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.
Ferreira-Gonzalez S, Lu WY, Raven A, Dwyer B, Man TY, O'Duibhir E, Lewis PJS, Campana L, Kendall TJ, Bird TG, Tarrats N, Acosta JC, Boulter L, Forbes SJ. Ferreira-Gonzalez S, et al. Among authors: o duibhir e. Nat Commun. 2018 Mar 9;9(1):1020. doi: 10.1038/s41467-018-03299-5. Nat Commun. 2018. PMID: 29523787 Free PMC article.
Alternatively activated macrophages promote resolution of necrosis following acute liver injury.
Starkey Lewis P, Campana L, Aleksieva N, Cartwright JA, Mackinnon A, O'Duibhir E, Kendall T, Vermeren M, Thomson A, Gadd V, Dwyer B, Aird R, Man TY, Rossi AG, Forrester L, Park BK, Forbes SJ. Starkey Lewis P, et al. Among authors: o duibhir e. J Hepatol. 2020 Aug;73(2):349-360. doi: 10.1016/j.jhep.2020.02.031. Epub 2020 Mar 11. J Hepatol. 2020. PMID: 32169610 Free PMC article.
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.
Campana L, Starkey Lewis PJ, Pellicoro A, Aucott RL, Man J, O'Duibhir E, Mok SE, Ferreira-Gonzalez S, Livingstone E, Greenhalgh SN, Hull KL, Kendall TJ, Vernimmen D, Henderson NC, Boulter L, Gregory CD, Feng Y, Anderton SM, Forbes SJ, Iredale JP. Campana L, et al. J Immunol. 2018 Feb 1;200(3):1169-1187. doi: 10.4049/jimmunol.1701247. Epub 2017 Dec 20. J Immunol. 2018. PMID: 29263216 Free PMC article.
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