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Prioritizing and selecting likely novel miRNAs from NGS data.
Backes C, Meder B, Hart M, Ludwig N, Leidinger P, Vogel B, Galata V, Roth P, Menegatti J, Grässer F, Ruprecht K, Kahraman M, Grossmann T, Haas J, Meese E, Keller A. Backes C, et al. Among authors: ruprecht k. Nucleic Acids Res. 2016 Apr 7;44(6):e53. doi: 10.1093/nar/gkv1335. Epub 2015 Dec 3. Nucleic Acids Res. 2016. PMID: 26635395 Free PMC article.
Toward the blood-borne miRNome of human diseases.
Keller A, Leidinger P, Bauer A, Elsharawy A, Haas J, Backes C, Wendschlag A, Giese N, Tjaden C, Ott K, Werner J, Hackert T, Ruprecht K, Huwer H, Huebers J, Jacobs G, Rosenstiel P, Dommisch H, Schaefer A, Müller-Quernheim J, Wullich B, Keck B, Graf N, Reichrath J, Vogel B, Nebel A, Jager SU, Staehler P, Amarantos I, Boisguerin V, Staehler C, Beier M, Scheffler M, Büchler MW, Wischhusen J, Haeusler SF, Dietl J, Hofmann S, Lenhof HP, Schreiber S, Katus HA, Rottbauer W, Meder B, Hoheisel JD, Franke A, Meese E. Keller A, et al. Among authors: ruprecht k. Nat Methods. 2011 Sep 4;8(10):841-3. doi: 10.1038/nmeth.1682. Nat Methods. 2011. PMID: 21892151
A blood based 12-miRNA signature of Alzheimer disease patients.
Leidinger P, Backes C, Deutscher S, Schmitt K, Mueller SC, Frese K, Haas J, Ruprecht K, Paul F, Stähler C, Lang CJ, Meder B, Bartfai T, Meese E, Keller A. Leidinger P, et al. Among authors: ruprecht k. Genome Biol. 2013 Jul 29;14(7):R78. doi: 10.1186/gb-2013-14-7-r78. Genome Biol. 2013. PMID: 23895045 Free PMC article.
Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis.
Keller A, Leidinger P, Meese E, Haas J, Backes C, Rasche L, Behrens JR, Pfuhl C, Wakonig K, Gieß RM, Jarius S, Meder B, Bellmann-Strobl J, Paul F, Pache FC, Ruprecht K. Keller A, et al. Among authors: ruprecht k. J Neuroinflammation. 2015 Oct 31;12:196. doi: 10.1186/s12974-015-0418-1. J Neuroinflammation. 2015. PMID: 26521232 Free PMC article.
Validating Alzheimer's disease micro RNAs using next-generation sequencing.
Keller A, Backes C, Haas J, Leidinger P, Maetzler W, Deuschle C, Berg D, Ruschil C, Galata V, Ruprecht K, Stähler C, Würstle M, Sickert D, Gogol M, Meder B, Meese E. Keller A, et al. Among authors: ruprecht k. Alzheimers Dement. 2016 May;12(5):565-76. doi: 10.1016/j.jalz.2015.12.012. Epub 2016 Jan 22. Alzheimers Dement. 2016. PMID: 26806387
462 results