Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacology.
Erickson RI, Tarrant J, Cain G, Lewin-Koh SC, Dybdal N, Wong H, Blackwood E, West K, Steigerwalt R, Mamounas M, Flygare JA, Amemiya K, Dambach D, Fairbrother WJ, Diaz D.
Erickson RI, et al.
Toxicol Sci. 2013 Jan;131(1):247-58. doi: 10.1093/toxsci/kfs265. Epub 2012 Sep 5.
Toxicol Sci. 2013.
PMID: 22956632