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Page 1
Dextran sulfate triggers platelet aggregation via direct activation of PEAR1.
Vandenbriele C, Sun Y, Criel M, Cludts K, Van Kerckhoven S, Izzi B, Vanassche T, Verhamme P, Hoylaerts MF. Vandenbriele C, et al. Among authors: hoylaerts mf. Platelets. 2016 Jun;27(4):365-72. doi: 10.3109/09537104.2015.1111321. Epub 2015 Nov 30. Platelets. 2016. PMID: 26619766
Absence of Pear1 does not affect murine platelet function in vivo.
Criel M, Izzi B, Vandenbriele C, Liesenborghs L, Van Kerckhoven S, Lox M, Cludts K, Jones EA, Vanassche T, Verhamme P, Hoylaerts M. Criel M, et al. Thromb Res. 2016 Oct;146:76-83. doi: 10.1016/j.thromres.2016.08.026. Epub 2016 Aug 26. Thromb Res. 2016. PMID: 27614188
A Human Platelet Receptor Protein Microarray Identifies the High Affinity Immunoglobulin E Receptor Subunit α (FcεR1α) as an Activating Platelet Endothelium Aggregation Receptor 1 (PEAR1) Ligand.
Sun Y, Vandenbriele C, Kauskot A, Verhamme P, Hoylaerts MF, Wright GJ. Sun Y, et al. Among authors: hoylaerts mf. Mol Cell Proteomics. 2015 May;14(5):1265-74. doi: 10.1074/mcp.M114.046946. Epub 2015 Feb 23. Mol Cell Proteomics. 2015. PMID: 25713122 Free PMC article.
A novel mechanism of sustained platelet αIIbβ3 activation via PEAR1.
Kauskot A, Di Michele M, Loyen S, Freson K, Verhamme P, Hoylaerts MF. Kauskot A, et al. Among authors: hoylaerts mf. Blood. 2012 Apr 26;119(17):4056-65. doi: 10.1182/blood-2011-11-392787. Epub 2012 Feb 27. Blood. 2012. PMID: 22371881 Free article.
PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway.
Kauskot A, Vandenbriele C, Louwette S, Gijsbers R, Tousseyn T, Freson K, Verhamme P, Hoylaerts MF. Kauskot A, et al. Among authors: hoylaerts mf. Blood. 2013 Jun 27;121(26):5208-17. doi: 10.1182/blood-2012-10-462887. Epub 2013 May 10. Blood. 2013. PMID: 23667054 Free article.
Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.
Vandenbriele C, Kauskot A, Vandersmissen I, Criel M, Geenens R, Craps S, Luttun A, Janssens S, Hoylaerts MF, Verhamme P. Vandenbriele C, et al. Among authors: hoylaerts mf. Cardiovasc Res. 2015 Oct 1;108(1):124-38. doi: 10.1093/cvr/cvv193. Epub 2015 Jul 7. Cardiovasc Res. 2015. PMID: 26156496
Allele-specific DNA methylation reinforces PEAR1 enhancer activity.
Izzi B, Pistoni M, Cludts K, Akkor P, Lambrechts D, Verfaillie C, Verhamme P, Freson K, Hoylaerts MF. Izzi B, et al. Among authors: hoylaerts mf. Blood. 2016 Aug 18;128(7):1003-12. doi: 10.1182/blood-2015-11-682153. Epub 2016 Jun 16. Blood. 2016. PMID: 27313330 Free article.
PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population.
Yang WY, Petit T, Cauwenberghs N, Zhang ZY, Sheng CS, Thijs L, Salvi E, Izzi B, Vandenbriele C, Wei FF, Gu YM, Jacobs L, Citterio L, Delli Carpini S, Barlassina C, Cusi D, Hoylaerts MF, Verhamme P, Kuznetsova T, Staessen JA. Yang WY, et al. Among authors: hoylaerts mf. BMC Med Genet. 2017 Apr 27;18(1):45. doi: 10.1186/s12881-017-0411-x. BMC Med Genet. 2017. PMID: 28449647 Free PMC article.
297 results