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Intracellular sphingosine releases calcium from lysosomes.
Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C. Höglinger D, et al. Among authors: galione a. Elife. 2015 Nov 27;4:e10616. doi: 10.7554/eLife.10616. Elife. 2015. PMID: 26613410 Free PMC article.
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.
Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A. Ruas M, et al. Among authors: galione a. Curr Biol. 2010 Apr 27;20(8):703-9. doi: 10.1016/j.cub.2010.02.049. Epub 2010 Mar 25. Curr Biol. 2010. PMID: 20346675 Free PMC article.
Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1.
Speak AO, Te Vruchte D, Davis LC, Morgan AJ, Smith DA, Yanjanin NM, Simmons L, Hartung R, Runz H, Mengel E, Beck M, Imrie J, Jacklin E, Wraith JE, Hendriksz C, Lachmann R, Cognet C, Sidhu R, Fujiwara H, Ory DS, Galione A, Porter FD, Vivier E, Platt FM. Speak AO, et al. Among authors: galione a. Blood. 2014 Jan 2;123(1):51-60. doi: 10.1182/blood-2013-03-488692. Epub 2013 Nov 14. Blood. 2014. PMID: 24235134 Free PMC article.
Imaging approaches to measuring lysosomal calcium.
Morgan AJ, Davis LC, Galione A. Morgan AJ, et al. Among authors: galione a. Methods Cell Biol. 2015;126:159-95. doi: 10.1016/bs.mcb.2014.10.031. Epub 2015 Jan 19. Methods Cell Biol. 2015. PMID: 25665446
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway.
Fineran P, Lloyd-Evans E, Lack NA, Platt N, Davis LC, Morgan AJ, Höglinger D, Tatituri RVV, Clark S, Williams IM, Tynan P, Al Eisa N, Nazarova E, Williams A, Galione A, Ory DS, Besra GS, Russell DG, Brenner MB, Sim E, Platt FM. Fineran P, et al. Among authors: galione a. Wellcome Open Res. 2016 Nov 18;1:18. doi: 10.12688/wellcomeopenres.10036.2. Wellcome Open Res. 2016. PMID: 28008422 Free PMC article.
Revealing the secrets of secretion.
Galione A, Davis LC. Galione A, et al. Elife. 2018 Nov 30;7:e43512. doi: 10.7554/eLife.43512. Elife. 2018. PMID: 30499445 Free PMC article.
238 results