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VE-cadherin is a critical endothelial regulator of TGF-beta signalling.
Rudini N, Felici A, Giampietro C, Lampugnani M, Corada M, Swirsding K, Garrè M, Liebner S, Letarte M, ten Dijke P, Dejana E. Rudini N, et al. EMBO J. 2008 Apr 9;27(7):993-1004. doi: 10.1038/emboj.2008.46. Epub 2008 Mar 13. EMBO J. 2008. PMID: 18337748 Free PMC article.
EndMT contributes to the onset and progression of cerebral cavernous malformations.
Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, Ferrarini L, Orsenigo F, Papa E, Boulday G, Tournier-Lasserve E, Chapon F, Richichi C, Retta SF, Lampugnani MG, Dejana E. Maddaluno L, et al. Among authors: lampugnani mg. Nature. 2013 Jun 27;498(7455):492-6. doi: 10.1038/nature12207. Epub 2013 Jun 9. Nature. 2013. PMID: 23748444
Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice.
Bravi L, Rudini N, Cuttano R, Giampietro C, Maddaluno L, Ferrarini L, Adams RH, Corada M, Boulday G, Tournier-Lasserve E, Dejana E, Lampugnani MG. Bravi L, et al. Among authors: lampugnani mg. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8421-6. doi: 10.1073/pnas.1501352112. Epub 2015 Jun 24. Proc Natl Acad Sci U S A. 2015. PMID: 26109568 Free PMC article.
The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling.
Giampietro C, Disanza A, Bravi L, Barrios-Rodiles M, Corada M, Frittoli E, Savorani C, Lampugnani MG, Boggetti B, Niessen C, Wrana JL, Scita G, Dejana E. Giampietro C, et al. Among authors: lampugnani mg. J Cell Biol. 2015 Dec 21;211(6):1177-92. doi: 10.1083/jcb.201501089. Epub 2015 Dec 14. J Cell Biol. 2015. PMID: 26668327 Free PMC article.
89 results