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Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury.
Thyfault JP, Rector RS, Uptergrove GM, Borengasser SJ, Morris EM, Wei Y, Laye MJ, Burant CF, Qi NR, Ridenhour SE, Koch LG, Britton SL, Ibdah JA. Thyfault JP, et al. Among authors: koch lg. J Physiol. 2009 Apr 15;587(Pt 8):1805-16. doi: 10.1113/jphysiol.2009.169060. Epub 2009 Feb 23. J Physiol. 2009. PMID: 19237421 Free PMC article.
Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis.
Morris EM, Jackman MR, Johnson GC, Liu TW, Lopez JL, Kearney ML, Fletcher JA, Meers GM, Koch LG, Britton SL, Rector RS, Ibdah JA, MacLean PS, Thyfault JP. Morris EM, et al. Among authors: koch lg. Am J Physiol Endocrinol Metab. 2014 Aug 15;307(4):E355-64. doi: 10.1152/ajpendo.00093.2014. Epub 2014 Jun 24. Am J Physiol Endocrinol Metab. 2014. PMID: 24961240 Free PMC article.
Aerobic capacity and hepatic mitochondrial lipid oxidation alters susceptibility for chronic high-fat diet-induced hepatic steatosis.
Morris EM, Meers GM, Koch LG, Britton SL, Fletcher JA, Fu X, Shankar K, Burgess SC, Ibdah JA, Rector RS, Thyfault JP. Morris EM, et al. Among authors: koch lg. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E749-E760. doi: 10.1152/ajpendo.00178.2016. Epub 2016 Sep 6. Am J Physiol Endocrinol Metab. 2016. PMID: 27600823 Free PMC article.
Aerobic metabolism underlies complexity and capacity.
Koch LG, Britton SL. Koch LG, et al. J Physiol. 2008 Jan 1;586(1):83-95. doi: 10.1113/jphysiol.2007.144709. Epub 2007 Oct 18. J Physiol. 2008. PMID: 17947307 Free PMC article. Review.
224 results