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Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity.
J Med Chem. 2015 Dec 24;58(24):9615-24. doi: 10.1021/acs.jmedchem.5b01456. Epub 2015 Dec 4.
J Med Chem. 2015.
PMID: 26571076
Free article.
PLGA nanoparticles and nanosuspensions with amphotericin B: Potent in vitro and in vivo alternatives to Fungizone and AmBisome.
Van de Ven H, Paulussen C, Feijens PB, Matheeussen A, Rombaut P, Kayaert P, Van den Mooter G, Weyenberg W, Cos P, Maes L, Ludwig A.
Van de Ven H, et al. Among authors: feijens pb.
J Control Release. 2012 Aug 10;161(3):795-803. doi: 10.1016/j.jconrel.2012.05.037. Epub 2012 May 26.
J Control Release. 2012.
PMID: 22641062
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Development of Novel Isoindolone-Based Compounds against Trypanosoma brucei rhodesiense.
Silva DG, Feijens PB, Hendrickx R, Matheeussen A, Grey L, Caljon G, Maes L, Emery FS, Junker A.
Silva DG, et al. Among authors: feijens pb.
ChemistryOpen. 2021 Sep;10(9):922-927. doi: 10.1002/open.202100180.
ChemistryOpen. 2021.
PMID: 34553828
Free PMC article.
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Exploration of 6-methyl-7-(Hetero)Aryl-7-Deazapurine ribonucleosides as antileishmanial agents.
Lin C, Karalic I, Matheeussen A, Feijens PB, Hulpia F, Maes L, Caljon G, Van Calenbergh S.
Lin C, et al. Among authors: feijens pb.
Eur J Med Chem. 2022 Jul 5;237:114367. doi: 10.1016/j.ejmech.2022.114367. Epub 2022 Apr 25.
Eur J Med Chem. 2022.
PMID: 35533570
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Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin.
Benramdane S, De Loose J, Filippi N, Espadinha M, Beyens O, Rymenant YV, Dirkx L, Bozdag M, Feijens PB, Augustyns K, Caljon G, De Winter H, De Meester I, Van der Veken P.
Benramdane S, et al. Among authors: feijens pb.
J Med Chem. 2023 Sep 28;66(18):12717-12738. doi: 10.1021/acs.jmedchem.3c00609. Epub 2023 Sep 18.
J Med Chem. 2023.
PMID: 37721854
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In Vivo Bioluminescence Imaging Reveals Differences in Leishmania infantum Parasite Killing Kinetics by Antileishmanial Reference Drugs.
Hendrickx S, Feijens PB, Escudié F, Chatelain E, Maes L, Caljon G.
Hendrickx S, et al. Among authors: feijens pb.
ACS Infect Dis. 2024 May 11. doi: 10.1021/acsinfecdis.4c00109. Online ahead of print.
ACS Infect Dis. 2024.
PMID: 38733389
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DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1.
Braillard S, Keenan M, Breese KJ, Heppell J, Abbott M, Islam R, Shackleford DM, Katneni K, Crighton E, Chen G, Patil R, Lee G, White KL, Carvalho S, Wall RJ, Chemi G, Zuccotto F, González S, Marco M, Deakyne J, Standing D, Brunori G, Lyon JJ, Castañeda-Casado P, Camino I, Martinez Martinez MS, Zulfiqar B, Avery VM, Feijens PB, Van Pelt N, Matheeussen A, Hendrickx S, Maes L, Caljon G, Yardley V, Wyllie S, Charman SA, Chatelain E.
Braillard S, et al. Among authors: feijens pb.
Sci Transl Med. 2023 Dec 13;15(726):eadh9902. doi: 10.1126/scitranslmed.adh9902. Epub 2023 Dec 13.
Sci Transl Med. 2023.
PMID: 38091406
Free PMC article.
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