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The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster.
Hoffmeister D, Ichinose K, Domann S, Faust B, Trefzer A, Dräger G, Kirschning A, Fischer C, Künzel E, Bearden D, Rohr J, Bechthold A. Hoffmeister D, et al. Among authors: bechthold a. Chem Biol. 2000 Nov;7(11):821-31. doi: 10.1016/s1074-5521(00)00029-6. Chem Biol. 2000. PMID: 11094336
Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics.
Weitnauer G, Mühlenweg A, Trefzer A, Hoffmeister D, Süssmuth RD, Jung G, Welzel K, Vente A, Girreser U, Bechthold A. Weitnauer G, et al. Among authors: bechthold a. Chem Biol. 2001 Jun;8(6):569-81. doi: 10.1016/s1074-5521(01)00040-0. Chem Biol. 2001. PMID: 11410376
Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic.
Trefzer A, Pelzer S, Schimana J, Stockert S, Bihlmaier C, Fiedler HP, Welzel K, Vente A, Bechthold A. Trefzer A, et al. Among authors: bechthold a. Antimicrob Agents Chemother. 2002 May;46(5):1174-82. doi: 10.1128/AAC.46.5.1174-1182.2002. Antimicrob Agents Chemother. 2002. PMID: 11959542 Free PMC article.
204 results