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A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.
Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M. Gustafsson M, et al. Among authors: lahesmaa r. Sci Transl Med. 2015 Nov 11;7(313):313ra178. doi: 10.1126/scitranslmed.aad2722. Sci Transl Med. 2015. PMID: 26560356 Free article.
Human embryonic stem cells are immunogenic in allogeneic and xenogeneic settings.
Grinnemo KH, Kumagai-Braesch M, Månsson-Broberg A, Skottman H, Hao X, Siddiqui A, Andersson A, Strömberg AM, Lahesmaa R, Hovatta O, Sylven C, Corbascio M, Dellgren G. Grinnemo KH, et al. Among authors: lahesmaa r. Reprod Biomed Online. 2006 Nov;13(5):712-24. doi: 10.1016/s1472-6483(10)60663-3. Reprod Biomed Online. 2006. PMID: 17169186
Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA.
Andrabi SBA, Kalim UU, Palani S, Khan MM, Khan MH, Fagersund J, Orpana J, Paulin N, Batkulwar K, Junttila S, Buchacher T, Grönroos T, Toikka L, Ammunet T, Sen P, Orešič M, Kumpulainen V, Tuomisto JEE, Sinha R, Marson A, Rasool O, Elo LL, Lahesmaa R. Andrabi SBA, et al. Among authors: lahesmaa r. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2315363121. doi: 10.1073/pnas.2315363121. Epub 2024 May 28. Proc Natl Acad Sci U S A. 2024. PMID: 38805281 Free article.
A proximal enhancer regulates RORA expression during early human Th17 cell differentiation.
Kalim UU, Biradar R, Junttila S, Khan MM, Tripathi S, Khan MH, Smolander J, Kanduri K, Envall T, Laiho A, Marson A, Rasool O, Elo LL, Lahesmaa R. Kalim UU, et al. Among authors: lahesmaa r. Clin Immunol. 2024 May 22;264:110261. doi: 10.1016/j.clim.2024.110261. Online ahead of print. Clin Immunol. 2024. PMID: 38788884 Free article.
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes.
Hendriks AEJ, Marcovecchio ML, Besser REJ, Bonifacio E, Casteels K, Elding Larsson H, Gemulla G, Lundgren M, Kordonouri O, Mallone R, Pociot F, Szypowska A, Toppari J, Berge TVD, Ziegler AG, Mathieu C, Achenbach P; INNODIA consortium, the Fr1da Study Group and the GPPAD Study Group. Hendriks AEJ, et al. Diabetes Metab Res Rev. 2024 Feb;40(2):e3777. doi: 10.1002/dmrr.3777. Diabetes Metab Res Rev. 2024. PMID: 38375753
262 results