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A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.
Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M. Gustafsson M, et al. Among authors: gawel dr. Sci Transl Med. 2015 Nov 11;7(313):313ra178. doi: 10.1126/scitranslmed.aad2722. Sci Transl Med. 2015. PMID: 26560356 Free article.
5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4(+) T Cells.
Nestor CE, Lentini A, Hägg Nilsson C, Gawel DR, Gustafsson M, Mattson L, Wang H, Rundquist O, Meehan RR, Klocke B, Seifert M, Hauck SM, Laumen H, Zhang H, Benson M. Nestor CE, et al. Among authors: gawel dr. Cell Rep. 2016 Jul 12;16(2):559-570. doi: 10.1016/j.celrep.2016.05.091. Epub 2016 Jun 23. Cell Rep. 2016. PMID: 27346350 Free PMC article.
Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis.
Hellberg S, Eklund D, Gawel DR, Köpsén M, Zhang H, Nestor CE, Kockum I, Olsson T, Skogh T, Kastbom A, Sjöwall C, Vrethem M, Håkansson I, Benson M, Jenmalm MC, Gustafsson M, Ernerudh J. Hellberg S, et al. Among authors: gawel dr. Cell Rep. 2016 Sep 13;16(11):2928-2939. doi: 10.1016/j.celrep.2016.08.036. Cell Rep. 2016. PMID: 27626663 Free article.
LASSIM-A network inference toolbox for genome-wide mechanistic modeling.
Magnusson R, Mariotti GP, Köpsén M, Lövfors W, Gawel DR, Jörnsten R, Linde J, Nordling TEM, Nyman E, Schulze S, Nestor CE, Zhang H, Cedersund G, Benson M, Tjärnberg A, Gustafsson M. Magnusson R, et al. Among authors: gawel dr. PLoS Comput Biol. 2017 Jun 22;13(6):e1005608. doi: 10.1371/journal.pcbi.1005608. eCollection 2017 Jun. PLoS Comput Biol. 2017. PMID: 28640810 Free PMC article.
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases.
Gawel DR, Serra-Musach J, Lilja S, Aagesen J, Arenas A, Asking B, Bengnér M, Björkander J, Biggs S, Ernerudh J, Hjortswang H, Karlsson JE, Köpsen M, Lee EJ, Lentini A, Li X, Magnusson M, Martínez-Enguita D, Matussek A, Nestor CE, Schäfer S, Seifert O, Sonmez C, Stjernman H, Tjärnberg A, Wu S, Åkesson K, Shalek AK, Stenmarker M, Zhang H, Gustafsson M, Benson M. Gawel DR, et al. Genome Med. 2019 Jul 30;11(1):47. doi: 10.1186/s13073-019-0657-3. Genome Med. 2019. PMID: 31358043 Free PMC article.
18 results