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Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.
Shailubhai K, Palejwala V, Arjunan KP, Saykhedkar S, Nefsky B, Foss JA, Comiskey S, Jacob GS, Plevy SE. Shailubhai K, et al. Among authors: plevy se. World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22. doi: 10.4292/wjgpt.v6.i4.213. World J Gastrointest Pharmacol Ther. 2015. PMID: 26558155 Free PMC article.
Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.
Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE. Steinbach EC, et al. Among authors: plevy se. J Immunol. 2014 Apr 15;192(8):3958-68. doi: 10.4049/jimmunol.1301533. Epub 2014 Mar 14. J Immunol. 2014. PMID: 24634494 Free PMC article.
Enteroendocrine cells express functional Toll-like receptors.
Bogunovic M, Davé SH, Tilstra JS, Chang DT, Harpaz N, Xiong H, Mayer LF, Plevy SE. Bogunovic M, et al. Among authors: plevy se. Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1770-83. doi: 10.1152/ajpgi.00249.2006. Epub 2007 Mar 29. Am J Physiol Gastrointest Liver Physiol. 2007. PMID: 17395901 Free PMC article.
NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity.
Kobayashi T, Matsuoka K, Sheikh SZ, Elloumi HZ, Kamada N, Hisamatsu T, Hansen JJ, Doty KR, Pope SD, Smale ST, Hibi T, Rothman PB, Kashiwada M, Plevy SE. Kobayashi T, et al. Among authors: plevy se. J Immunol. 2011 Apr 15;186(8):4649-55. doi: 10.4049/jimmunol.1003888. Epub 2011 Mar 7. J Immunol. 2011. PMID: 21383239 Free PMC article.
NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis.
Kobayashi T, Steinbach EC, Russo SM, Matsuoka K, Nochi T, Maharshak N, Borst LB, Hostager B, Garcia-Martinez JV, Rothman PB, Kashiwada M, Sheikh SZ, Murray PJ, Plevy SE. Kobayashi T, et al. Among authors: plevy se. J Immunol. 2014 Feb 15;192(4):1918-27. doi: 10.4049/jimmunol.1301819. Epub 2014 Jan 17. J Immunol. 2014. PMID: 24442434 Free PMC article.
109 results