Merchant KM - Search Results

1

Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.

Kim KH, Liu J, Sells Galvin RJ, Dage JL, Egeland JA, Smith RC, Merchant KM, Paul SM. Kim KH, et al. Among authors: merchant km. PLoS One. 2015 Nov 10;10(11):e0142693. doi: 10.1371/journal.pone.0142693. eCollection 2015. PLoS One. 2015. PMID: 26554713 Free PMC article.

2

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons.

Dage JL, Colvin EM, Fouillet A, Langron E, Roell WC, Li J, Mathur SX, Mogg AJ, Schmitt MG, Felder CC, Merchant KM, Isaac J, Broad LM, Sher E, Ursu D. Dage JL, et al. Among authors: merchant km. Psychopharmacology (Berl). 2014 Mar;231(6):1105-24. doi: 10.1007/s00213-013-3384-2. Epub 2014 Jan 16. Psychopharmacology (Berl). 2014. PMID: 24429870

3

Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.

Wang H, Li Y, Ryder JW, Hole JT, Ebert PJ, Airey DC, Qian HR, Logsdon B, Fisher A, Ahmed Z, Murray TK, Cavallini A, Bose S, Eastwood BJ, Collier DA, Dage JL, Miller BB, Merchant KM, O'Neill MJ, Demattos RB. Wang H, et al. Among authors: merchant km. Mol Neurodegener. 2018 Dec 17;13(1):65. doi: 10.1186/s13024-018-0296-y. Mol Neurodegener. 2018. PMID: 30558641 Free PMC article.

4

Increased brain bio-distribution and chemical stability and decreased immunogenicity of an engineered variant of GDNF.

Smith RC, O'Bryan LM, Mitchell PJ, Leung D, Ghanem M, Wilson JM, Hanson JC, Sossick S, Cooper J, Huang L, Merchant KM, Lu J, O'Neill MJ. Smith RC, et al. Among authors: merchant km. Exp Neurol. 2015 May;267:165-76. doi: 10.1016/j.expneurol.2015.03.002. Epub 2015 Mar 12. Exp Neurol. 2015. PMID: 25771799 Free article.

5

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.

Schadt EE, Buchanan S, Brennand KJ, Merchant KM. Schadt EE, et al. Among authors: merchant km. Front Pharmacol. 2014 Dec 2;5:252. doi: 10.3389/fphar.2014.00252. eCollection 2014. Front Pharmacol. 2014. PMID: 25520658 Free PMC article. Review.

6

Neuroreplacement, growth factor, and small molecule neurotrophic approaches for treating Parkinson's disease.

O'Neill MJ, Messenger MJ, Lakics V, Murray TK, Karran EH, Szekeres PG, Nisenbaum ES, Merchant KM. O'Neill MJ, et al. Among authors: merchant km. Int Rev Neurobiol. 2007;77:179-217. doi: 10.1016/S0074-7742(06)77006-4. Int Rev Neurobiol. 2007. PMID: 17178475 Review. No abstract available.

7

Pharmacological characterization of cGMP regulation by the biarylpropylsulfonamide class of positive, allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

Ryder JW, Falcone JF, Manro JR, Svensson KA, Merchant KM. Ryder JW, et al. Among authors: merchant km. J Pharmacol Exp Ther. 2006 Oct;319(1):293-8. doi: 10.1124/jpet.106.105734. Epub 2006 Jun 27. J Pharmacol Exp Ther. 2006. PMID: 16803862

8

Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry.

Kellie JF, Higgs RE, Ryder JW, Major A, Beach TG, Adler CH, Merchant K, Knierman MD. Kellie JF, et al. Sci Rep. 2014 Jul 23;4:5797. doi: 10.1038/srep05797. Sci Rep. 2014. PMID: 25052239 Free PMC article.

9

Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain.

Ursu D, Ebert P, Langron E, Ruble C, Munsie L, Zou W, Fijal B, Qian YW, McNearney TA, Mogg A, Grubisha O, Merchant K, Sher E. Ursu D, et al. Mol Pain. 2014 Jun 16;10:37. doi: 10.1186/1744-8069-10-37. Mol Pain. 2014. PMID: 24934217 Free PMC article.

10

Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.

Perry KW, Falcone JF, Fell MJ, Ryder JW, Yu H, Love PL, Katner J, Gordon KD, Wade MR, Man T, Nomikos GG, Phebus LA, Cauvin AJ, Johnson KW, Jones CK, Hoffmann BJ, Sandusky GE, Walter MW, Porter WJ, Yang L, Merchant KM, Shannon HE, Svensson KA. Perry KW, et al. Among authors: merchant km. Neuropharmacology. 2008 Oct;55(5):743-54. doi: 10.1016/j.neuropharm.2008.06.016. Epub 2008 Jun 17. Neuropharmacology. 2008. PMID: 18602930

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