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Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRα genotype evaluated by next generation sequencing (NGS).
Saponara M, Urbini M, Astolfi A, Indio V, Ercolani G, Del Gaudio M, Santini D, Pirini MG, Fiorentino M, Nannini M, Lolli C, Mandrioli A, Gatto L, Brandi G, Biasco G, Pinna AD, Pantaleo MA. Saponara M, et al. Oncotarget. 2015 Dec 8;6(39):42243-57. doi: 10.18632/oncotarget.6278. Oncotarget. 2015. PMID: 26544626 Free PMC article.
A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number.
Astolfi A, Nannini M, Pantaleo MA, Di Battista M, Heinrich MC, Santini D, Catena F, Corless CL, Maleddu A, Saponara M, Lolli C, Di Scioscio V, Formica S, Biasco G. Astolfi A, et al. Among authors: saponara m. Lab Invest. 2010 Sep;90(9):1285-94. doi: 10.1038/labinvest.2010.110. Epub 2010 Jun 14. Lab Invest. 2010. PMID: 20548289 Free article.
Impressive long-term disease stabilization by nilotinib in two pretreated patients with KIT/PDGFRA wild-type metastatic gastrointestinal stromal tumours.
Pantaleo MA, Nannini M, Saponara M, Gnocchi C, Di Scioscio V, Lolli C, Catena F, Astolfi A, Di Battista M, Biasco G; GIST Study Group, University of Bologna, Bologna, Italy. Pantaleo MA, et al. Among authors: saponara m. Anticancer Drugs. 2012 Jun;23(5):567-72. doi: 10.1097/CAD.0b013e328352cc50. Anticancer Drugs. 2012. PMID: 22430048
Analysis of all subunits, SDHA, SDHB, SDHC, SDHD, of the succinate dehydrogenase complex in KIT/PDGFRA wild-type GIST.
Pantaleo MA, Astolfi A, Urbini M, Nannini M, Paterini P, Indio V, Saponara M, Formica S, Ceccarelli C, Casadio R, Rossi G, Bertolini F, Santini D, Pirini MG, Fiorentino M, Basso U, Biasco G; GIST Study Group. Pantaleo MA, et al. Among authors: saponara m. Eur J Hum Genet. 2014 Jan;22(1):32-9. doi: 10.1038/ejhg.2013.80. Epub 2013 Apr 24. Eur J Hum Genet. 2014. PMID: 23612575 Free PMC article.
Good survival outcome of metastatic SDH-deficient gastrointestinal stromal tumors harboring SDHA mutations.
Pantaleo MA, Lolli C, Nannini M, Astolfi A, Indio V, Saponara M, Urbini M, La Rovere S, Gill A, Goldstein D, Ceccarelli C, Santini D, Rossi G, Fiorentino M, Di Scioscio V, Fusaroli P, Mandrioli A, Gatto L, Catena F, Basso U, Ercolani G, Pinna AD, Biasco G. Pantaleo MA, et al. Among authors: saponara m. Genet Med. 2015 May;17(5):391-5. doi: 10.1038/gim.2014.115. Epub 2014 Sep 4. Genet Med. 2015. PMID: 25188872 Free article.
Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).
Nannini M, Astolfi A, Urbini M, Indio V, Santini D, Heinrich MC, Corless CL, Ceccarelli C, Saponara M, Mandrioli A, Lolli C, Ercolani G, Brandi G, Biasco G, Pantaleo MA. Nannini M, et al. Among authors: saponara m. BMC Cancer. 2014 Sep 20;14:685. doi: 10.1186/1471-2407-14-685. BMC Cancer. 2014. PMID: 25239601 Free PMC article.
112 results