Yea K - Search Results

1

Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates.

Lerner RA, Grover RK, Zhang H, Xie J, Han KH, Peng Y, Yea K. Lerner RA, et al. Among authors: yea k. Q Rev Biophys. 2015 Nov;48(4):389-94. doi: 10.1017/S0033583515000049. Q Rev Biophys. 2015. PMID: 26537396 Review.

2

Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells.

Xie J, Zhang H, Yea K, Lerner RA. Xie J, et al. Among authors: yea k. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8099-104. doi: 10.1073/pnas.1306263110. Epub 2013 Apr 23. Proc Natl Acad Sci U S A. 2013. PMID: 23613575 Free PMC article.

3

Selecting agonists from single cells infected with combinatorial antibody libraries.

Zhang H, Yea K, Xie J, Ruiz D, Wilson IA, Lerner RA. Zhang H, et al. Among authors: yea k. Chem Biol. 2013 May 23;20(5):734-41. doi: 10.1016/j.chembiol.2013.04.012. Chem Biol. 2013. PMID: 23706638

4

Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections.

Yea K, Zhang H, Xie J, Jones TM, Yang G, Song BD, Lerner RA. Yea K, et al. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14966-71. doi: 10.1073/pnas.1313671110. Epub 2013 Aug 26. Proc Natl Acad Sci U S A. 2013. PMID: 23980154 Free PMC article.

5

Prevention of cell death by antibodies selected from intracellular combinatorial libraries.

Xie J, Yea K, Zhang H, Moldt B, He L, Zhu J, Lerner RA. Xie J, et al. Among authors: yea k. Chem Biol. 2014 Feb 20;21(2):274-83. doi: 10.1016/j.chembiol.2013.12.006. Epub 2014 Jan 16. Chem Biol. 2014. PMID: 24440080

6

Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic.

Yea K, Xie J, Zhang H, Zhang W, Lerner RA. Yea K, et al. Curr Opin Chem Biol. 2015 Jun;26:1-7. doi: 10.1016/j.cbpa.2015.01.002. Epub 2015 Jan 23. Curr Opin Chem Biol. 2015. PMID: 25621729 Review.

7

Agonist antibody that induces human malignant cells to kill one another.

Yea K, Zhang H, Xie J, Jones TM, Lin CW, Francesconi W, Berton F, Fallahi M, Sauer K, Lerner RA. Yea K, et al. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6158-65. doi: 10.1073/pnas.1519079112. Epub 2015 Oct 20. Proc Natl Acad Sci U S A. 2015. PMID: 26487683 Free PMC article.

8

Activating pleiotropic receptors to kill cancer cells.

Yea K, Zhang H, Lerner RA. Yea K, et al. Cell Cycle. 2016;15(2):158-9. doi: 10.1080/15384101.2015.1118912. Epub 2015 Nov 20. Cell Cycle. 2016. PMID: 26588245 Free PMC article. No abstract available.

9

Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects.

Zhang H, Sturchler E, Zhu J, Nieto A, Cistrone PA, Xie J, He L, Yea K, Jones T, Turn R, Di Stefano PS, Griffin PR, Dawson PE, McDonald PH, Lerner RA. Zhang H, et al. Among authors: yea k. Nat Commun. 2015 Dec 1;6:8918. doi: 10.1038/ncomms9918. Nat Commun. 2015. PMID: 26621478 Free PMC article.

10

Autocrine-Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries.

Zhang H, Du M, Xie J, Liu X, Sun J, Wang W, Xin X, Possani LD, Yea K, Lerner RA. Zhang H, et al. Among authors: yea k. Angew Chem Int Ed Engl. 2016 Aug 1;55(32):9306-10. doi: 10.1002/anie.201603052. Epub 2016 May 20. Angew Chem Int Ed Engl. 2016. PMID: 27197631

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