Dunn SE - Search Results

1

Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells.

Castellana B, Aasen T, Moreno-Bueno G, Dunn SE, Ramón y Cajal S. Castellana B, et al. Among authors: dunn se. Oncotarget. 2015 Nov 10;6(35):38239-56. doi: 10.18632/oncotarget.5664. Oncotarget. 2015. PMID: 26512918 Free PMC article.

2

Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells.

Davies AH, Reipas K, Hu K, Berns R, Firmino N, Stratford AL, Dunn SE. Davies AH, et al. Among authors: dunn se. Oncotarget. 2015 Aug 21;6(24):20570-7. doi: 10.18632/oncotarget.4135. Oncotarget. 2015. PMID: 26011941 Free PMC article.

3

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1).

Reipas KM, Law JH, Couto N, Islam S, Li Y, Li H, Cherkasov A, Jung K, Cheema AS, Jones SJ, Hassell JA, Dunn SE. Reipas KM, et al. Among authors: dunn se. Oncotarget. 2013 Feb;4(2):329-45. doi: 10.18632/oncotarget.834. Oncotarget. 2013. PMID: 23593654 Free PMC article.

4

YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention.

Davies AH, Dunn SE. Davies AH, et al. Among authors: dunn se. Oncotarget. 2011 May;2(5):401-6. doi: 10.18632/oncotarget.276. Oncotarget. 2011. PMID: 21576761 Free PMC article.

5

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition.

Mohan P, Castellsague J, Jiang J, Allen K, Chen H, Nemirovsky O, Spyra M, Hu K, Kluwe L, Pujana MA, Villanueva A, Mautner VF, Keats JJ, Dunn SE, Lazaro C, Maxwell CA. Mohan P, et al. Among authors: dunn se. Oncotarget. 2013 Jan;4(1):80-93. doi: 10.18632/oncotarget.793. Oncotarget. 2013. PMID: 23328114 Free PMC article.

6

YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.

Davies AH, Reipas KM, Pambid MR, Berns R, Stratford AL, Fotovati A, Firmino N, Astanehe A, Hu K, Maxwell C, Mills GB, Dunn SE. Davies AH, et al. Among authors: dunn se. Stem Cells. 2014 Jun;32(6):1437-50. doi: 10.1002/stem.1707. Stem Cells. 2014. PMID: 24648416 Free PMC article.

7

The expression of activated Y-box binding protein-1 serine 102 mediates trastuzumab resistance in breast cancer cells by increasing CD44+ cells.

Dhillon J, Astanehe A, Lee C, Fotovati A, Hu K, Dunn SE. Dhillon J, et al. Among authors: dunn se. Oncogene. 2010 Nov 25;29(47):6294-300. doi: 10.1038/onc.2010.365. Epub 2010 Aug 30. Oncogene. 2010. PMID: 20802512

8

Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells.

Finkbeiner MR, Astanehe A, To K, Fotovati A, Davies AH, Zhao Y, Jiang H, Stratford AL, Shadeo A, Boccaccio C, Comoglio P, Mertens PR, Eirew P, Raouf A, Eaves CJ, Dunn SE. Finkbeiner MR, et al. Among authors: dunn se. Oncogene. 2009 Mar 19;28(11):1421-31. doi: 10.1038/onc.2008.485. Epub 2009 Jan 19. Oncogene. 2009. PMID: 19151767

9

YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification.

Davies AH, Barrett I, Pambid MR, Hu K, Stratford AL, Freeman S, Berquin IM, Pelech S, Hieter P, Maxwell C, Dunn SE. Davies AH, et al. Among authors: dunn se. Oncogene. 2011 Aug 25;30(34):3649-60. doi: 10.1038/onc.2011.82. Epub 2011 Mar 21. Oncogene. 2011. PMID: 21423216 Free PMC article.

10

Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy.

Stratford AL, Habibi G, Astanehe A, Jiang H, Hu K, Park E, Shadeo A, Buys TP, Lam W, Pugh T, Marra M, Nielsen TO, Klinge U, Mertens PR, Aparicio S, Dunn SE. Stratford AL, et al. Among authors: dunn se. Breast Cancer Res. 2007;9(5):R61. doi: 10.1186/bcr1767. Breast Cancer Res. 2007. PMID: 17875215 Free PMC article.

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