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ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.
Kijas AW, Lim YC, Bolderson E, Cerosaletti K, Gatei M, Jakob B, Tobias F, Taucher-Scholz G, Gueven N, Oakley G, Concannon P, Wolvetang E, Khanna KK, Wiesmüller L, Lavin MF. Kijas AW, et al. Among authors: gatei m. Nucleic Acids Res. 2015 Sep 30;43(17):8352-67. doi: 10.1093/nar/gkv754. Epub 2015 Aug 3. Nucleic Acids Res. 2015. PMID: 26240375 Free PMC article.
Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage.
Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF. Quek H, et al. Among authors: gatei m. J Leukoc Biol. 2017 Apr;101(4):927-947. doi: 10.1189/jlb.4VMA0716-316R. Epub 2016 Nov 28. J Leukoc Biol. 2017. PMID: 27895165
A patient-derived olfactory stem cell disease model for ataxia-telangiectasia.
Stewart R, Kozlov S, Matigian N, Wali G, Gatei M, Sutharsan R, Bellette B, Wraith-Kijas A, Cochrane J, Coulthard M, Perry C, Sinclair K, Mackay-Sim A, Lavin MF. Stewart R, et al. Among authors: gatei m. Hum Mol Genet. 2013 Jun 15;22(12):2495-509. doi: 10.1093/hmg/ddt101. Epub 2013 Mar 7. Hum Mol Genet. 2013. PMID: 23474819
A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.
Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF. Quek H, et al. Among authors: gatei m. Hum Mol Genet. 2017 Jan 1;26(1):109-123. doi: 10.1093/hmg/ddw371. Hum Mol Genet. 2017. PMID: 28007901
49 results