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A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype.
Oncotarget. 2015 Nov 24;6(37):40005-25. doi: 10.18632/oncotarget.5552.
Oncotarget. 2015.
PMID: 26503466
Free PMC article.
ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance.
Conrad C, Benzel J, Dorzweiler K, Cook L, Schlomann U, Zarbock A, Slater EP, Nimsky C, Bartsch JW.
Conrad C, et al. Among authors: dorzweiler k.
Clin Sci (Lond). 2019 Jan 11;133(1):83-99. doi: 10.1042/CS20180906. Print 2019 Jan 15.
Clin Sci (Lond). 2019.
PMID: 30635388
Review.
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Metalloprotease inhibitor profiles of human ADAM8 in vitro and in cell-based assays.
Schlomann U, Dorzweiler K, Nuti E, Tuccinardi T, Rossello A, Bartsch JW.
Schlomann U, et al. Among authors: dorzweiler k.
Biol Chem. 2019 May 27;400(6):801-810. doi: 10.1515/hsz-2018-0396.
Biol Chem. 2019.
PMID: 30738011
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Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.
Conrad C, Dorzweiler K, Miller MA, Lauffenburger DA, Strik H, Bartsch JW.
Conrad C, et al. Among authors: dorzweiler k.
Fluids Barriers CNS. 2017 Aug 14;14(1):22. doi: 10.1186/s12987-017-0070-5.
Fluids Barriers CNS. 2017.
PMID: 28806983
Free PMC article.
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