Podust VN - Search Results

1

Extension of in vivo half-life of biologically active molecules by XTEN protein polymers.

Podust VN, Balan S, Sim BC, Coyle MP, Ernst U, Peters RT, Schellenberger V. Podust VN, et al. J Control Release. 2016 Oct 28;240:52-66. doi: 10.1016/j.jconrel.2015.10.038. Epub 2015 Oct 30. J Control Release. 2016. PMID: 26497931 Free article. Review.

2

Extension of in vivo half-life of biologically active peptides via chemical conjugation to XTEN protein polymer.

Podust VN, Sim BC, Kothari D, Henthorn L, Gu C, Wang CW, McLaughlin B, Schellenberger V. Podust VN, et al. Protein Eng Des Sel. 2013 Nov;26(11):743-53. doi: 10.1093/protein/gzt048. Epub 2013 Oct 16. Protein Eng Des Sel. 2013. PMID: 24133142

3

Multivalent antiviral XTEN-peptide conjugates with long in vivo half-life and enhanced solubility.

Ding S, Song M, Sim BC, Gu C, Podust VN, Wang CW, McLaughlin B, Shah TP, Lax R, Gast R, Sharan R, Vasek A, Hartman MA, Deniston C, Srinivas P, Schellenberger V. Ding S, et al. Among authors: podust vn. Bioconjug Chem. 2014 Jul 16;25(7):1351-9. doi: 10.1021/bc500215m. Epub 2014 Jun 23. Bioconjug Chem. 2014. PMID: 24932887 Free PMC article.

4

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's disease model.

Alters SE, McLaughlin B, Spink B, Lachinyan T, Wang CW, Podust V, Schellenberger V, Stemmer WP. Alters SE, et al. PLoS One. 2012;7(11):e50630. doi: 10.1371/journal.pone.0050630. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189208 Free PMC article.

5

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's. PLoS One. 2012; 7(11): e50630.

Alters SE, McLaughlin B, Spink B, Lachinyan T, Wang CW, Podust V, Schellenberger V, Stemmer WP. Alters SE, et al. PLoS One. 2013 Jun 10;8(6):10.1371/annotation/5c7138bd-5602-466d-8daf-e75e0b7d7fdb. doi: 10.1371/annotation/5c7138bd-5602-466d-8daf-e75e0b7d7fdb. Print 2013. PLoS One. 2013. PMID: 23762221 Free PMC article.

6

A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides.

Zacharias N, Podust VN, Kajihara KK, Leipold D, Del Rosario G, Thayer D, Dong E, Paluch M, Fischer D, Zheng K, Lei C, He J, Ng C, Su D, Liu L, Masih S, Sawyer W, Tinianow J, Marik J, Yip V, Li G, Chuh J, Morisaki JH, Park S, Zheng B, Hernandez-Barry H, Loyet KM, Xu M, Kozak KR, Phillips GL, Shen BQ, Wu C, Xu K, Yu SF, Kamath A, Rowntree RK, Reilly D, Pillow T, Polson A, Schellenberger V, Hazenbos WLW, Sadowsky J. Zacharias N, et al. Among authors: podust vn. Chem Sci. 2022 Jan 28;13(11):3147-3160. doi: 10.1039/d1sc05243h. eCollection 2022 Mar 16. Chem Sci. 2022. PMID: 35414872 Free PMC article.

7

A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination.

Podust VN, Brownell JE, Gladysheva TB, Luo RS, Wang C, Coggins MB, Pierce JW, Lightcap ES, Chau V. Podust VN, et al. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4579-84. doi: 10.1073/pnas.090465597. Proc Natl Acad Sci U S A. 2000. PMID: 10781063 Free PMC article.

8

ProteinChip array profiling for identification of disease- and chemotherapy-associated biomarkers of nasopharyngeal carcinoma.

Cho WC, Yip TT, Ngan RK, Yip TT, Podust VN, Yip C, Yiu HH, Yip V, Cheng WW, Ma VW, Law SC. Cho WC, et al. Among authors: podust vn. Clin Chem. 2007 Feb;53(2):241-50. doi: 10.1373/clinchem.2005.065805. Epub 2007 Jan 2. Clin Chem. 2007. PMID: 17200135

9

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha.

Read MA, Brownell JE, Gladysheva TB, Hottelet M, Parent LA, Coggins MB, Pierce JW, Podust VN, Luo RS, Chau V, Palombella VJ. Read MA, et al. Among authors: podust vn. Mol Cell Biol. 2000 Apr;20(7):2326-33. doi: 10.1128/MCB.20.7.2326-2333.2000. Mol Cell Biol. 2000. PMID: 10713156 Free PMC article.

10

Preanalytic influence of sample handling on SELDI-TOF serum protein profiles.

Timms JF, Arslan-Low E, Gentry-Maharaj A, Luo Z, T'Jampens D, Podust VN, Ford J, Fung ET, Gammerman A, Jacobs I, Menon U. Timms JF, et al. Among authors: podust vn. Clin Chem. 2007 Apr;53(4):645-56. doi: 10.1373/clinchem.2006.080101. Epub 2007 Feb 15. Clin Chem. 2007. PMID: 17303688

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