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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ. Zhang Y, et al. Among authors: patel da, patel ac. Nat Immunol. 2015 Dec;16(12):1215-27. doi: 10.1038/ni.3279. Epub 2015 Oct 19. Nat Immunol. 2015. PMID: 26479788 Free PMC article.
Host epithelial-viral interactions as cause and cure for asthma.
Holtzman MJ, Patel DA, Zhang Y, Patel AC. Holtzman MJ, et al. Among authors: patel da, patel ac. Curr Opin Immunol. 2011 Aug;23(4):487-94. doi: 10.1016/j.coi.2011.05.010. Epub 2011 Jun 22. Curr Opin Immunol. 2011. PMID: 21703838 Free PMC article. Review.
Immune pathways for translating viral infection into chronic airway disease.
Holtzman MJ, Byers DE, Benoit LA, Battaile JT, You Y, Agapov E, Park C, Grayson MH, Kim EY, Patel AC. Holtzman MJ, et al. Among authors: patel ac. Adv Immunol. 2009;102:245-76. doi: 10.1016/S0065-2776(09)01205-X. Adv Immunol. 2009. PMID: 19477323 Free PMC article. Review.
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease.
Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit LA, Byers DE, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, Polineni D, Patterson GA, Schwendener RA, Allard JD, Peltz G, Holtzman MJ. Kim EY, et al. Among authors: patel ac. Nat Med. 2008 Jun;14(6):633-40. doi: 10.1038/nm1770. Epub 2008 May 18. Nat Med. 2008. PMID: 18488036 Free PMC article.
115 results