Stott LA - Search Results

1

Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data.

Stott LA, Hall DA, Holliday ND. Stott LA, et al. Biochem Pharmacol. 2016 Feb 1;101:1-12. doi: 10.1016/j.bcp.2015.10.011. Epub 2015 Oct 23. Biochem Pharmacol. 2016. PMID: 26478533 Review.

2

Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D₂ receptors.

Sykes DA, Moore H, Stott L, Holliday N, Javitch JA, Lane JR, Charlton SJ. Sykes DA, et al. Nat Commun. 2017 Oct 2;8(1):763. doi: 10.1038/s41467-017-00716-z. Nat Commun. 2017. PMID: 28970469 Free PMC article.

3

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists.

Yrjölä S, Parkkari T, Navia-Paldanius D, Laitinen T, Kaczor AA, Kokkola T, Adusei-Mensah F, Savinainen JR, Laitinen JT, Poso A, Alexander A, Penman J, Stott L, Anskat M, Irving AJ, Nevalainen TJ. Yrjölä S, et al. Eur J Med Chem. 2016 Jan 1;107:119-32. doi: 10.1016/j.ejmech.2015.10.050. Epub 2015 Nov 2. Eur J Med Chem. 2016. PMID: 26575458

4

The Neutrophil Dynamic Mass Redistribution Assay as a Medium throughput Primary Cell Screening Assay.

Stott LA, la Rochelle AD, Brown S, Osborne G, Hutchings CJ, Poulter S, Bennett KA, Barnes M. Stott LA, et al. J Pharmacol Exp Ther. 2024 Mar 15;389(1):19-31. doi: 10.1124/jpet.123.001787. J Pharmacol Exp Ther. 2024. PMID: 37863490

5

The Identification of GPR52 Agonist HTL0041178, a Potential Therapy for Schizophrenia and Related Psychiatric Disorders.

Poulter S, Austin N, Armstrong R, Barnes M, Bucknell SJ, Higueruelo A, Banerjee J, Mead A, Mould R, MacSweeney C, O'Brien MA, Stott LA, Watson SP. Poulter S, et al. Among authors: stott la. ACS Med Chem Lett. 2023 Mar 14;14(4):499-505. doi: 10.1021/acsmedchemlett.3c00052. eCollection 2023 Apr 13. ACS Med Chem Lett. 2023. PMID: 37077397 Free PMC article.

6

Optical observation of single spins in silicon.

Higginbottom DB, Kurkjian ATK, Chartrand C, Kazemi M, Brunelle NA, MacQuarrie ER, Klein JR, Lee-Hone NR, Stacho J, Ruether M, Bowness C, Bergeron L, DeAbreu A, Harrigan SR, Kanaganayagam J, Marsden DW, Richards TS, Stott LA, Roorda S, Morse KJ, Thewalt MLW, Simmons S. Higginbottom DB, et al. Among authors: stott la. Nature. 2022 Jul;607(7918):266-270. doi: 10.1038/s41586-022-04821-y. Epub 2022 Jul 13. Nature. 2022. PMID: 35831600

7

Characterisation of inverse agonism of the orphan-G protein-coupled receptor GPR52 by cannabinoid ligands Cannabidiol and O-1918.

Stott LA, Brighton CA, Brown J, Mould R, Bennett KA, Newman R, Currinn H, Autore F, Higueruelo AP, Tehan BG, MacSweeney C, O'Brien MA, Watson SP. Stott LA, et al. Heliyon. 2021 Jun 1;7(6):e07201. doi: 10.1016/j.heliyon.2021.e07201. eCollection 2021 Jun. Heliyon. 2021. PMID: 34189291 Free PMC article.

8

Lowering water oxidation overpotentials using the ionisable imidazole of copper(2-(2'-pyridyl)imidazole).

Stott LA, Prosser KE, Berdichevsky EK, Walsby CJ, Warren JJ. Stott LA, et al. Chem Commun (Camb). 2017 Jan 3;53(3):651-654. doi: 10.1039/c6cc09208j. Chem Commun (Camb). 2017. PMID: 27990513

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