Holmes AP - Search Results

1

Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.

Bailey LD, Kalyana Sundaram RV, Li H, Duffy C, Aneja R, Rosemary Bastian A, Holmes AP, Kamanna K, Rashad AA, Chaiken I. Bailey LD, et al. Among authors: holmes ap. ACS Chem Biol. 2015 Dec 18;10(12):2861-73. doi: 10.1021/acschembio.5b00381. Epub 2015 Oct 22. ACS Chem Biol. 2015. PMID: 26458166 Free PMC article.

2

Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy.

Emileh A, Duffy C, Holmes AP, Rosemary Bastian A, Aneja R, Tuzer F, Rajagopal S, Li H, Abrams CF, Chaiken IM. Emileh A, et al. Among authors: holmes ap. Biochemistry. 2014 Jun 3;53(21):3403-14. doi: 10.1021/bi500136f. Epub 2014 May 19. Biochemistry. 2014. PMID: 24801282 Free PMC article.

3

Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.

Rashad AA, Acharya K, Haftl A, Aneja R, Dick A, Holmes AP, Chaiken I. Rashad AA, et al. Among authors: holmes ap. Org Biomol Chem. 2017 Sep 26;15(37):7770-7782. doi: 10.1039/c7ob01448a. Org Biomol Chem. 2017. PMID: 28770939 Free PMC article.

4

Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators.

Zhang S, Holmes AP, Dick A, Rashad AA, Enríquez Rodríguez L, Canziani GA, Root MJ, Chaiken IM. Zhang S, et al. Among authors: holmes ap. Retrovirology. 2021 Oct 9;18(1):31. doi: 10.1186/s12977-021-00575-z. Retrovirology. 2021. PMID: 34627310 Free PMC article.

5

HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism.

Tuzer F, Madani N, Kamanna K, Zentner I, LaLonde J, Holmes A, Upton E, Rajagopal S, McFadden K, Contarino M, Sodroski J, Chaiken I. Tuzer F, et al. Proteins. 2013 Feb;81(2):271-90. doi: 10.1002/prot.24184. Epub 2012 Oct 26. Proteins. 2013. PMID: 23011758 Free PMC article.

6

Non-natural peptide triazole antagonists of HIV-1 envelope gp120.

Kamanna K, Aneja R, Duffy C, Kubinski P, Rodrigo Moreira D, Bailey LD, McFadden K, Schön A, Holmes A, Tuzer F, Contarino M, Freire E, Chaiken IM. Kamanna K, et al. ChemMedChem. 2013 Feb;8(2):322-8. doi: 10.1002/cmdc.201200422. Epub 2012 Dec 13. ChemMedChem. 2013. PMID: 23239505 Free PMC article.

7

Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation.

Rosemary Bastian A, Nangarlia A, Bailey LD, Holmes A, Kalyana Sundaram RV, Ang C, Moreira DR, Freedman K, Duffy C, Contarino M, Abrams C, Root M, Chaiken I. Rosemary Bastian A, et al. J Biol Chem. 2015 Jan 2;290(1):529-43. doi: 10.1074/jbc.M114.608315. Epub 2014 Nov 4. J Biol Chem. 2015. PMID: 25371202 Free PMC article.

8

Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface.

Rashad AA, Song LR, Holmes AP, Acharya K, Zhang S, Wang ZL, Gary E, Xie X, Pirrone V, Kutzler MA, Long YQ, Chaiken I. Rashad AA, et al. Among authors: holmes ap. J Med Chem. 2018 Jun 14;61(11):5020-5033. doi: 10.1021/acs.jmedchem.8b00477. Epub 2018 Jun 1. J Med Chem. 2018. PMID: 29767965 Free PMC article.

9

Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse.

Sommerfeld LC, Holmes AP, Yu TY, O'Shea C, Kavanagh DM, Pike JM, Wright T, Syeda F, Aljehani A, Kew T, Cardoso VR, Kabir SN, Hepburn C, Menon PR, Broadway-Stringer S, O'Reilly M, Witten A, Fortmueller L, Lutz S, Kulle A, Gkoutos GV, Pavlovic D, Arlt W, Lavery GG, Steeds R, Gehmlich K, Stoll M, Kirchhof P, Fabritz L. Sommerfeld LC, et al. Among authors: holmes ap. J Physiol. 2024 Feb 12. doi: 10.1113/JP284597. Online ahead of print. J Physiol. 2024. PMID: 38345865

10

Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model.

Cumberland MJ, Euchner J, Azad AJ, T N Vo N, Kirchhof P, Holmes AP, Denning C, Gehmlich K. Cumberland MJ, et al. Among authors: holmes ap. F1000Res. 2024 Feb 12;12:1224. doi: 10.12688/f1000research.139482.1. eCollection 2023. F1000Res. 2024. PMID: 38298530 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

101 results

Search Page