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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW. Mostoslavsky R, et al. Among authors: mostoslavsky g. Cell. 2006 Jan 27;124(2):315-29. doi: 10.1016/j.cell.2005.11.044. Cell. 2006. PMID: 16439206 Free article.
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA. Oberdoerffer P, et al. Among authors: mostoslavsky r. Cell. 2008 Nov 28;135(5):907-18. doi: 10.1016/j.cell.2008.10.025. Cell. 2008. PMID: 19041753 Free PMC article.
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.
Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R. Zhong L, et al. Among authors: mostoslavsky r. Cell. 2010 Jan 22;140(2):280-93. doi: 10.1016/j.cell.2009.12.041. Cell. 2010. PMID: 20141841 Free PMC article.
SIRT3 in calorie restriction: can you hear me now?
Sebastian C, Mostoslavsky R. Sebastian C, et al. Among authors: mostoslavsky r. Cell. 2010 Nov 24;143(5):667-8. doi: 10.1016/j.cell.2010.11.009. Cell. 2010. PMID: 21111225 Free article.
SIRT3 deacetylase: the Jekyll and Hyde sirtuin.
Silberman DM, Mostoslavsky R. Silberman DM, et al. Among authors: mostoslavsky r. EMBO Rep. 2011 Jul 8;12(8):746-7. doi: 10.1038/embor.2011.147. EMBO Rep. 2011. PMID: 21738223 Free PMC article. No abstract available.
117 results