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Ure(k)a! Sirtuins Regulate Mitochondria.
Hallows WC, Smith BC, Lee S, Denu JM. Hallows WC, et al. Among authors: denu jm. Cell. 2009 May 1;137(3):404-6. doi: 10.1016/j.cell.2009.04.036. Cell. 2009. PMID: 19410538 Free PMC article.
Catalysis and mechanistic insights into sirtuin activation.
Dittenhafer-Reed KE, Feldman JL, Denu JM. Dittenhafer-Reed KE, et al. Among authors: denu jm. Chembiochem. 2011 Jan 24;12(2):281-9. doi: 10.1002/cbic.201000434. Epub 2010 Nov 9. Chembiochem. 2011. PMID: 21243715 Free PMC article. Review.
Structure and biochemical functions of SIRT6.
Pan PW, Feldman JL, Devries MK, Dong A, Edwards AM, Denu JM. Pan PW, et al. Among authors: denu jm. J Biol Chem. 2011 Apr 22;286(16):14575-87. doi: 10.1074/jbc.M111.218990. Epub 2011 Mar 1. J Biol Chem. 2011. PMID: 21362626 Free PMC article.
Sirtuin catalysis and regulation.
Feldman JL, Dittenhafer-Reed KE, Denu JM. Feldman JL, et al. Among authors: denu jm. J Biol Chem. 2012 Dec 14;287(51):42419-27. doi: 10.1074/jbc.R112.378877. Epub 2012 Oct 18. J Biol Chem. 2012. PMID: 23086947 Free PMC article. Review.
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.
Dominy JE Jr, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, Puigserver P. Dominy JE Jr, et al. Among authors: denu jm. Mol Cell. 2012 Dec 28;48(6):900-13. doi: 10.1016/j.molcel.2012.09.030. Epub 2012 Nov 8. Mol Cell. 2012. PMID: 23142079 Free PMC article.
204 results