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c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer's disease.
León R, Gutiérrez DA, Pinto C, Morales C, de la Fuente C, Riquelme C, Cortés BI, González-Martin A, Chamorro D, Espinosa N, Fuentealba P, Cancino GI, Zanlungo S, Dulcey AE, Marugan JJ, Álvarez Rojas A. León R, et al. Among authors: cancino gi. Front Aging Neurosci. 2023 Jun 5;15:1180987. doi: 10.3389/fnagi.2023.1180987. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37358955 Free PMC article.
Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice.
Chandía-Cristi A, Gutiérrez DA, Dulcey AE, Lara M, Vargas L, Lin YH, Jimenez-Muñoz P, Larenas G, Xu X, Wang A, Owens A, Dextras C, Chen Y, Pinto C, Marín T, Almarza-Salazar H, Acevedo K, Cancino GI, Hu X, Rojas P, Ferrer M, Southall N, Henderson MJ, Zanlungo S, Marugan JJ, Álvarez R A. Chandía-Cristi A, et al. Among authors: cancino gi. Cell Rep. 2024 May 28;43(5):114144. doi: 10.1016/j.celrep.2024.114144. Epub 2024 Apr 23. Cell Rep. 2024. PMID: 38656874 Free article.
c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.
Martinez A, Lamaizon CM, Valls C, Llambi F, Leal N, Fitzgerald P, Guy C, Kamiński MM, Inestrosa NC, van Zundert B, Cancino GI, Dulcey AE, Zanlungo S, Marugan JJ, Hetz C, Green DR, Alvarez AR. Martinez A, et al. Among authors: cancino gi. Antioxidants (Basel). 2023 Nov 16;12(11):2007. doi: 10.3390/antiox12112007. Antioxidants (Basel). 2023. PMID: 38001860 Free PMC article.
29 results