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Anti-tumor activity of lipophilic imidazolium salts on select NSCLC cell lines.
Wright BD, Deblock MC, Wagers PO, Duah E, Robishaw NK, Shelton KL, Southerland MR, DeBord MA, Kersten KM, McDonald LJ, Stiel JA, Panzner MJ, Tessier CA, Paruchuri S, Youngs WJ. Wright BD, et al. Among authors: duah e. Med Chem Res. 2015 Jul;24(7):2838-2861. doi: 10.1007/s00044-015-1330-z. Epub 2015 Feb 13. Med Chem Res. 2015. PMID: 26446298 Free PMC article.
Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.
Kondeti V, Al-Azzam N, Duah E, Thodeti CK, Boyce JA, Paruchuri S. Kondeti V, et al. Among authors: duah e. J Allergy Clin Immunol. 2016 Jan;137(1):289-298. doi: 10.1016/j.jaci.2015.06.030. Epub 2015 Aug 5. J Allergy Clin Immunol. 2016. PMID: 26255103 Free PMC article.
Mechanosensitive transient receptor potential vanilloid 4 regulates Dermatophagoides farinae-induced airway remodeling via 2 distinct pathways modulating matrix synthesis and degradation.
Gombedza F, Kondeti V, Al-Azzam N, Koppes S, Duah E, Patil P, Hexter M, Phillips D, Thodeti CK, Paruchuri S. Gombedza F, et al. Among authors: duah e. FASEB J. 2017 Apr;31(4):1556-1570. doi: 10.1096/fj.201601045R. Epub 2017 Jan 10. FASEB J. 2017. PMID: 28073835 Free PMC article.
Thus, our results support a unique role for TRPV4 in D. farinae-induced airway remodeling and warrant further studies in humans for it to be used as a novel therapeutic target in the treatment of asthma.-Gombedza, F., Kondeti, V., Al-Azzam, N., Koppes, S., Duah, E., …
Thus, our results support a unique role for TRPV4 in D. farinae-induced airway remodeling and warrant further studies in humans for it to be …
27 results