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Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cells.
Dragoni S, Reforgiato M, Zuccolo E, Poletto V, Lodola F, Ruffinatti FA, Bonetti E, Guerra G, Barosi G, Rosti V, Moccia F. Dragoni S, et al. Among authors: ruffinatti fa. Exp Hematol. 2015 Dec;43(12):1019-1030.e3. doi: 10.1016/j.exphem.2015.09.002. Epub 2015 Oct 19. Exp Hematol. 2015. PMID: 26432919 Free article. Clinical Trial.
VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells.
Lodola F, Laforenza U, Cattaneo F, Ruffinatti FA, Poletto V, Massa M, Tancredi R, Zuccolo E, Khdar DA, Riccardi A, Biggiogera M, Rosti V, Guerra G, Moccia F. Lodola F, et al. Among authors: ruffinatti fa. Oncotarget. 2017 Aug 14;8(56):95223-95246. doi: 10.18632/oncotarget.20255. eCollection 2017 Nov 10. Oncotarget. 2017. PMID: 29221123 Free PMC article.
Deletion of calcineurin from GFAP-expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na+ /K+ ATPase.
Tapella L, Soda T, Mapelli L, Bortolotto V, Bondi H, Ruffinatti FA, Dematteis G, Stevano A, Dionisi M, Ummarino S, Di Ruscio A, Distasi C, Grilli M, Genazzani AA, D'Angelo E, Moccia F, Lim D. Tapella L, et al. Among authors: ruffinatti fa. Glia. 2020 Mar;68(3):543-560. doi: 10.1002/glia.23737. Epub 2019 Oct 18. Glia. 2020. PMID: 31626368 Free article.
Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice.
Dematteis G, Vydmantaitė G, Ruffinatti FA, Chahin M, Farruggio S, Barberis E, Ferrari E, Marengo E, Distasi C, Morkūnienė R, Genazzani AA, Grilli M, Grossini E, Corazzari M, Manfredi M, Lim D, Jekabsone A, Tapella L. Dematteis G, et al. Among authors: ruffinatti fa. Cell Death Dis. 2020 Aug 18;11(8):645. doi: 10.1038/s41419-020-02911-1. Cell Death Dis. 2020. PMID: 32811809 Free PMC article.
Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures.
Tapella L, Dematteis G, Ruffinatti FA, Ponzoni L, Fiordaliso F, Corbelli A, Albanese E, Pistolato B, Pagano J, Barberis E, Marengo E, Balducci C, Forloni G, Verpelli C, Sala C, Distasi C, Sala M, Manfredi M, Genazzani AA, Lim D. Tapella L, et al. Among authors: ruffinatti fa. Cell Calcium. 2021 Dec;100:102480. doi: 10.1016/j.ceca.2021.102480. Epub 2021 Sep 26. Cell Calcium. 2021. PMID: 34607180
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