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LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro.
Jiang L, Brackeva B, Stangé G, Verhaeghen K, Costa O, Couillard-Després S, Rotheneichner P, Aigner L, Van Schravendijk C, Pipeleers D, Ling Z, Gorus F, Martens GA. Jiang L, et al. Among authors: verhaeghen k. J Proteomics. 2013 Mar 27;80:268-80. doi: 10.1016/j.jprot.2012.12.031. Epub 2013 Jan 19. J Proteomics. 2013. PMID: 23337804
Potential of UCHL1 as biomarker for destruction of pancreatic beta cells.
Brackeva B, De Punt V, Kramer G, Costa O, Verhaeghen K, Stangé G, Sadones J, Xavier C, Aerts JM, Gorus FK, Martens GA. Brackeva B, et al. Among authors: verhaeghen k. J Proteomics. 2015 Mar 18;117:156-67. doi: 10.1016/j.jprot.2015.01.009. Epub 2015 Jan 29. J Proteomics. 2015. PMID: 25638021
Protein markers for insulin-producing beta cells with higher glucose sensitivity.
Martens GA, Jiang L, Verhaeghen K, Connolly JB, Geromanos SG, Stangé G, Van Oudenhove L, Devreese B, Hellemans KH, Ling Z, Van Schravendijk C, Pipeleers DG, Vissers JP, Gorus FK. Martens GA, et al. Among authors: verhaeghen k. PLoS One. 2010 Dec 6;5(12):e14214. doi: 10.1371/journal.pone.0014214. PLoS One. 2010. PMID: 21151894 Free PMC article.
Hyperglycemic clamp and oral glucose tolerance test for 3-year prediction of clinical onset in persistently autoantibody-positive offspring and siblings of type 1 diabetic patients.
Balti EV, Vandemeulebroucke E, Weets I, Van De Velde U, Van Dalem A, Demeester S, Verhaeghen K, Gillard P, De Block C, Ruige J, Keymeulen B, Pipeleers DG, Decochez K, Gorus FK; Belgian Diabetes Registry. Balti EV, et al. Among authors: verhaeghen k. J Clin Endocrinol Metab. 2015 Feb;100(2):551-60. doi: 10.1210/jc.2014-2035. Epub 2014 Nov 18. J Clin Endocrinol Metab. 2015. PMID: 25405499 Free article.
An important minority of prediabetic first-degree relatives of type 1 diabetic patients derives from seroconversion to persistent autoantibody positivity after 10 years of age.
Vermeulen I, Weets I, Costa O, Asanghanwa M, Verhaeghen K, Decochez K, Ruige J, Casteels K, Wenzlau J, Hutton JC, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Vermeulen I, et al. Among authors: verhaeghen k. Diabetologia. 2012 Feb;55(2):413-20. doi: 10.1007/s00125-011-2376-1. Epub 2011 Nov 18. Diabetologia. 2012. PMID: 22095238 Free PMC article.
Clinical and biological characteristics of diabetic patients under age 40 in Cameroon: relation to autoantibody status and comparison with Belgian patients.
Asanghanwa M, Gorus FK, Weets I, der Auwera BV, Aminkeng F, Mbunwe E, Goubert P, Verhaeghen K, Sobngwi E, Wenzlau JM, Hutton JC, Pipeleers DG, Keymeulen B, Mbanya JC, van Schravendijk C. Asanghanwa M, et al. Among authors: verhaeghen k. Diabetes Res Clin Pract. 2014 Jan;103(1):97-105. doi: 10.1016/j.diabres.2013.11.013. Epub 2013 Nov 20. Diabetes Res Clin Pract. 2014. PMID: 24332797 Free PMC article.
Preexisting insulin autoantibodies predict efficacy of otelixizumab in preserving residual β-cell function in recent-onset type 1 diabetes.
Demeester S, Keymeulen B, Kaufman L, Van Dalem A, Balti EV, Van de Velde U, Goubert P, Verhaeghen K, Davidson HW, Wenzlau JM, Weets I, Pipeleers DG, Gorus FK. Demeester S, et al. Among authors: verhaeghen k. Diabetes Care. 2015 Apr;38(4):644-51. doi: 10.2337/dc14-1575. Epub 2015 Jan 12. Diabetes Care. 2015. PMID: 25583753 Free PMC article. Clinical Trial.
22 results