FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.
Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, Mohammed A, Hugosson F, Zhang H, Hsu AW, Halenbeck R, Hallberg B, Palmer RH.
Guan J, et al. Among authors: hallberg b.
Elife. 2015 Sep 29;4:e09811. doi: 10.7554/eLife.09811.
Elife. 2015.
PMID: 26418745
Free PMC article.
Aberrant activation of anaplastic lymphoma kinase (ALK) has been described in a range of human cancers, including non-small cell lung cancer and neuroblastoma (Hallberg and Palmer, 2013). Vertebrate ALK has been considered to be an orphan receptor and the identity of the A …
Aberrant activation of anaplastic lymphoma kinase (ALK) has been described in a range of human cancers, including non-small cell lung cancer …