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Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways.
Horiuchi D, Huskey NE, Kusdra L, Wohlbold L, Merrick KA, Zhang C, Creasman KJ, Shokat KM, Fisher RP, Goga A. Horiuchi D, et al. Among authors: goga a. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1019-27. doi: 10.1073/pnas.1111317109. Epub 2012 Apr 3. Proc Natl Acad Sci U S A. 2012. PMID: 22474407 Free PMC article.
MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer.
Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, Goga A. Lim L, et al. Among authors: goga a. Hepatology. 2014 Jan;59(1):202-15. doi: 10.1002/hep.26662. Epub 2013 Nov 22. Hepatology. 2014. PMID: 23913442 Free PMC article.
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.
Olive V, Sabio E, Bennett MJ, De Jong CS, Biton A, McGann JC, Greaney SK, Sodir NM, Zhou AY, Balakrishnan A, Foth M, Luftig MA, Goga A, Speed TP, Xuan Z, Evan GI, Wan Y, Minella AC, He L. Olive V, et al. Among authors: goga a. Elife. 2013 Oct 15;2:e00822. doi: 10.7554/eLife.00822. Elife. 2013. PMID: 24137534 Free PMC article.
Taking on challenging targets: making MYC druggable.
Horiuchi D, Anderton B, Goga A. Horiuchi D, et al. Among authors: goga a. Am Soc Clin Oncol Educ Book. 2014:e497-502. doi: 10.14694/EdBook_AM.2014.34.e497. Am Soc Clin Oncol Educ Book. 2014. PMID: 24857145 Free PMC article. Review.
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.
Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S. Martins MM, et al. Among authors: goga a. Cancer Discov. 2015 Feb;5(2):154-67. doi: 10.1158/2159-8290.CD-14-0552. Epub 2014 Dec 12. Cancer Discov. 2015. PMID: 25501949 Free PMC article.
263 results