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Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.
Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM. Coughlan MT, et al. Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28. Diabetes. 2016. PMID: 26822084
SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy: SGLT2 PROTEIN INHIBITION DECREASES RENAL LIPID ACCUMULATION, INFLAMMATION, AND THE DEVELOPMENT OF NEPHROPATHY IN DIABETIC MICE.
Wang XX, Levi J, Luo Y, Myakala K, Herman-Edelstein M, Qiu L, Wang D, Peng Y, Grenz A, Lucia S, Dobrinskikh E, D'Agati VD, Koepsell H, Kopp JB, Rosenberg AZ, Levi M. Wang XX, et al. J Biol Chem. 2017 Mar 31;292(13):5335-5348. doi: 10.1074/jbc.M117.779520. Epub 2017 Feb 14. J Biol Chem. 2017. PMID: 28196866 Free PMC article.
TGFβ1-dependent podocyte dysfunction.
Herman-Edelstein M, Weinstein T, Gafter U. Herman-Edelstein M, et al. Curr Opin Nephrol Hypertens. 2013 Jan;22(1):93-9. doi: 10.1097/MNH.0b013e32835b4870. Curr Opin Nephrol Hypertens. 2013. PMID: 23132369 Review.
35 results