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Trypanocidal activity of marine natural products.
Jones AJ, Grkovic T, Sykes ML, Avery VM. Jones AJ, et al. Mar Drugs. 2013 Oct 22;11(10):4058-82. doi: 10.3390/md11104058. Mar Drugs. 2013. PMID: 24152565 Free PMC article. Review.
Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.
Russell S, Rahmani R, Jones AJ, Newson HL, Neilde K, Cotillo I, Rahmani Khajouei M, Ferrins L, Qureishi S, Nguyen N, Martinez-Martinez MS, Weaver DF, Kaiser M, Riley J, Thomas J, De Rycker M, Read KD, Flematti GR, Ryan E, Tanghe S, Rodriguez A, Charman SA, Kessler A, Avery VM, Baell JB, Piggott MJ. Russell S, et al. Among authors: jones aj. J Med Chem. 2016 Nov 10;59(21):9686-9720. doi: 10.1021/acs.jmedchem.6b00442. Epub 2016 Sep 19. J Med Chem. 2016. PMID: 27548560 Free article.
Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi.
Varghese S, Rahmani R, Russell S, Deora GS, Ferrins L, Toynton A, Jones A, Sykes M, Kessler A, Eufrásio A, Cordeiro AT, Sherman J, Rodriguez A, Avery VM, Piggott MJ, Baell JB. Varghese S, et al. ACS Med Chem Lett. 2019 Sep 9;11(3):278-285. doi: 10.1021/acsmedchemlett.9b00218. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184957 Free PMC article.
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
Ferrins L, Rahmani R, Sykes ML, Jones AJ, Avery VM, Teston E, Almohaywi B, Yin J, Smith J, Hyland C, White KL, Ryan E, Campbell M, Charman SA, Kaiser M, Baell JB. Ferrins L, et al. Among authors: jones aj. Eur J Med Chem. 2013 Aug;66:450-65. doi: 10.1016/j.ejmech.2013.05.007. Epub 2013 May 16. Eur J Med Chem. 2013. PMID: 23831695
198 results