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Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension.
Uschner FE, Ranabhat G, Choi SS, Granzow M, Klein S, Schierwagen R, Raskopf E, Gautsch S, van der Ven PF, Fürst DO, Strassburg CP, Sauerbruch T, Diehl AM, Trebicka J. Uschner FE, et al. Among authors: strassburg cp. Sci Rep. 2015 Sep 28;5:14573. doi: 10.1038/srep14573. Sci Rep. 2015. PMID: 26412302 Free PMC article.
A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease.
Nischalke HD, Lutz P, Krämer B, Söhne J, Müller T, Rosendahl J, Fischer J, Berg T, Hittatiya K, Fischer HP, Soyka M, Semmo N, Nattermann J, Sauerbruch T, Strassburg CP, Stickel F, Spengler U. Nischalke HD, et al. Among authors: strassburg cp. J Hepatol. 2014 Nov;61(5):1073-9. doi: 10.1016/j.jhep.2014.06.006. Epub 2014 Jun 16. J Hepatol. 2014. PMID: 24946282
A farnesoid X receptor polymorphism predisposes to spontaneous bacterial peritonitis.
Lutz P, Berger C, Langhans B, Grünhage F, Appenrodt B, Nattermann J, Lammert F, Hoerauf A, Sauerbruch T, Strassburg CP, Spengler U, Nischalke HD. Lutz P, et al. Among authors: strassburg cp. Dig Liver Dis. 2014 Nov;46(11):1047-50. doi: 10.1016/j.dld.2014.07.008. Epub 2014 Jul 30. Dig Liver Dis. 2014. PMID: 25086996
452 results