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Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.
Alves TC, Pongratz RL, Zhao X, Yarborough O, Sereda S, Shirihai O, Cline GW, Mason G, Kibbey RG. Alves TC, et al. Among authors: shirihai o. Cell Metab. 2015 Nov 3;22(5):936-47. doi: 10.1016/j.cmet.2015.08.021. Epub 2015 Sep 24. Cell Metab. 2015. PMID: 26411341 Free PMC article.
Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos.
Jesinkey SR, Madiraju AK, Alves TC, Yarborough OH, Cardone RL, Zhao X, Parsaei Y, Nasiri AR, Butrico G, Liu X, Molina AJ, Rountree AM, Neal AS, Wolf DM, Sterpka J, Philbrick WM, Sweet IR, Shirihai OH, Kibbey RG. Jesinkey SR, et al. Cell Rep. 2019 Jul 16;28(3):759-772.e10. doi: 10.1016/j.celrep.2019.06.058. Cell Rep. 2019. PMID: 31315053 Free PMC article.
Pro-inflammatory macrophage activation does not require inhibition of mitochondrial respiration.
Ball AB, Jones AE, Nguyễn KB, Rios A, Marx N, Hsieh WY, Yang K, Desousa BR, Kim KKO, Veliova M, Del Mundo ZM, Shirihai OS, Benincá C, Stiles L, Bensinger SJ, Divakaruni AS. Ball AB, et al. Among authors: shirihai os. bioRxiv [Preprint]. 2024 May 14:2024.05.10.593451. doi: 10.1101/2024.05.10.593451. bioRxiv. 2024. PMID: 38798678 Free PMC article. Preprint.
PGC-1α drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity.
Varuzhanyan G, Chen CC, Freeland J, He T, Tran W, Song K, Wang L, Cheng D, Xu S, Dibernardo GA, Esedebe FN, Abt ER, Park JW, Memarzadeh S, Graeber T, Shirihai O, Witte O. Varuzhanyan G, et al. Among authors: shirihai o. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588489. doi: 10.1101/2024.04.09.588489. bioRxiv. 2024. PMID: 38645232 Free PMC article. Preprint.
Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis.
Rodriguez LR, Alysandratos KD, Katzen J, Murthy A, Barboza WR, Tomer Y, Acin-Perez R, Petcherski A, Minakin K, Carson P, Iyer S, Chavez K, Cooper CH, Babu A, Weiner AI, Vaughan AE, Arany Z, Shirihai OS, Kotton DN, Beers MF. Rodriguez LR, et al. Among authors: shirihai os. bioRxiv [Preprint]. 2024 Mar 28:2024.03.26.586649. doi: 10.1101/2024.03.26.586649. bioRxiv. 2024. PMID: 38585863 Free PMC article. Preprint.
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria.
Zhou Z, Ma A, Moore TM, Wolf DM, Yang N, Tran P, Segawa M, Strumwasser AR, Ren W, Fu K, Wanagat J, van der Bliek AM, Crosbie-Watson R, Liesa M, Stiles L, Acin-Perez R, Mahata S, Shirihai O, Goodarzi MO, Handzlik M, Metallo CM, Walker DW, Hevener AL. Zhou Z, et al. Among authors: shirihai o. Sci Adv. 2024 Apr 5;10(14):eadl0389. doi: 10.1126/sciadv.adl0389. Epub 2024 Apr 3. Sci Adv. 2024. PMID: 38569044 Free PMC article.
A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity.
Mosharov EV, Rosenberg AM, Monzel AS, Osto CA, Stiles L, Rosoklija GB, Dwork AJ, Bindra S, Zhang Y, Fujita M, Mariani MB, Bakalian M, Sulzer D, De Jager PL, Menon V, Shirihai OS, Mann JJ, Underwood M, Boldrini M, Thiebaut de Schotten M, Picard M. Mosharov EV, et al. Among authors: shirihai os. Res Sq [Preprint]. 2024 Mar 22:rs.3.rs-4047706. doi: 10.21203/rs.3.rs-4047706/v1. Res Sq. 2024. PMID: 38562777 Free PMC article. Preprint.
A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity.
Mosharov EV, Rosenberg AM, Monzel AS, Osto CA, Stiles L, Rosoklija GB, Dwork AJ, Bindra S, Zhang Y, Fujita M, Mariani MB, Bakalian M, Sulzer D, De Jager PL, Menon V, Shirihai OS, Mann JJ, Underwood M, Boldrini M, de Schotten MT, Picard M. Mosharov EV, et al. Among authors: shirihai os. bioRxiv [Preprint]. 2024 Mar 7:2024.03.05.583623. doi: 10.1101/2024.03.05.583623. bioRxiv. 2024. PMID: 38496679 Free PMC article. Preprint.
189 results