Willbold D - Search Results

1

QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.

Brener O, Dunkelmann T, Gremer L, van Groen T, Mirecka EA, Kadish I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelt F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. Brener O, et al. Among authors: willbold d. Sci Rep. 2015 Sep 23;5:13222. doi: 10.1038/srep13222. Sci Rep. 2015. PMID: 26394756 Free PMC article.

2

Purification of recombinantly expressed and cytotoxic human amyloid-beta peptide 1-42.

Wiesehan K, Funke SA, Fries M, Willbold D. Wiesehan K, et al. Among authors: willbold d. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):229-33. doi: 10.1016/j.jchromb.2007.06.003. Epub 2007 Jun 14. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17606418

3

Single particle detection of Abeta aggregates associated with Alzheimer's disease.

Funke SA, Birkmann E, Henke F, Görtz P, Lange-Asschenfeldt C, Riesner D, Willbold D. Funke SA, et al. Among authors: willbold d. Biochem Biophys Res Commun. 2007 Dec 28;364(4):902-7. doi: 10.1016/j.bbrc.2007.10.085. Epub 2007 Oct 24. Biochem Biophys Res Commun. 2007. PMID: 17963690

4

Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide.

Wiesehan K, Stöhr J, Nagel-Steger L, van Groen T, Riesner D, Willbold D. Wiesehan K, et al. Among authors: willbold d. Protein Eng Des Sel. 2008 Apr;21(4):241-6. doi: 10.1093/protein/gzm054. Epub 2008 Feb 5. Protein Eng Des Sel. 2008. PMID: 18252750

5

An ultrasensitive assay for diagnosis of Alzheimer's disease.

Funke SA, Birkmann E, Henke F, Görtz P, Lange-Asschenfeldt C, Riesner D, Willbold D. Funke SA, et al. Among authors: willbold d. Rejuvenation Res. 2008 Apr;11(2):315-8. doi: 10.1089/rej.2008.0670. Rejuvenation Res. 2008. PMID: 18328004

6

A highly sensitive diagnostic assay for aggregate-related diseases, including prion diseases and Alzheimer's disease.

Birkmann E, Henke F, Funke SA, Bannach O, Riesner D, Willbold D. Birkmann E, et al. Among authors: willbold d. Rejuvenation Res. 2008 Apr;11(2):359-63. doi: 10.1089/rej.2008.0697. Rejuvenation Res. 2008. PMID: 18442323

7

Reduction of Alzheimer's disease amyloid plaque load in transgenic mice by D3, A D-enantiomeric peptide identified by mirror image phage display.

van Groen T, Wiesehan K, Funke SA, Kadish I, Nagel-Steger L, Willbold D. van Groen T, et al. Among authors: willbold d. ChemMedChem. 2008 Dec;3(12):1848-52. doi: 10.1002/cmdc.200800273. ChemMedChem. 2008. PMID: 19016284 No abstract available.

8

In vitro and in vivo staining characteristics of small, fluorescent, Abeta42-binding D-enantiomeric peptides in transgenic AD mouse models.

van Groen T, Kadish I, Wiesehan K, Funke SA, Willbold D. van Groen T, et al. Among authors: willbold d. ChemMedChem. 2009 Feb;4(2):276-82. doi: 10.1002/cmdc.200800289. ChemMedChem. 2009. PMID: 19072935

9

Transient reduction of spontaneous neuronal network activity by sublethal amyloid beta (1-42) peptide concentrations.

Görtz P, Opatz J, Siebler M, Funke SA, Willbold D, Lange-Asschenfeldt C. Görtz P, et al. Among authors: willbold d. J Neural Transm (Vienna). 2009 Mar;116(3):351-5. doi: 10.1007/s00702-009-0188-y. Epub 2009 Feb 13. J Neural Transm (Vienna). 2009. PMID: 19214376

10

Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker.

Nagel-Steger L, Demeler B, Meyer-Zaika W, Hochdörffer K, Schrader T, Willbold D. Nagel-Steger L, et al. Among authors: willbold d. Eur Biophys J. 2010 Feb;39(3):415-22. doi: 10.1007/s00249-009-0416-2. Epub 2009 Feb 24. Eur Biophys J. 2010. PMID: 19238376

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