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Immune- and miRNA-response to recombinant interferon beta-1a: a biomarker evaluation study to guide the development of novel type I interferon- based therapies.
Coenen M, Hinze AV, Mengel M, Fuhrmann C, Lüdenbach B, Zimmermann J, Dykstra V, Fimmers R, Viviani R, Stingl J, Holdenrieder S, Müller M, Hartmann G, Coch C. Coenen M, et al. Among authors: hartmann g. BMC Pharmacol Toxicol. 2015 Sep 22;16:25. doi: 10.1186/s40360-015-0025-x. BMC Pharmacol Toxicol. 2015. PMID: 26392348 Free PMC article. Clinical Trial.
Approaching the RNA ligand for RIG-I?
Schlee M, Hartmann E, Coch C, Wimmenauer V, Janke M, Barchet W, Hartmann G. Schlee M, et al. Among authors: hartmann g, hartmann e. Immunol Rev. 2009 Jan;227(1):66-74. doi: 10.1111/j.1600-065X.2008.00724.x. Immunol Rev. 2009. PMID: 19120476 Review.
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O, Akira S, Tuschl T, Latz E, Ludwig J, Hartmann G. Schlee M, et al. Among authors: hartmann g. Immunity. 2009 Jul 17;31(1):25-34. doi: 10.1016/j.immuni.2009.05.008. Epub 2009 Jul 2. Immunity. 2009. PMID: 19576794 Free PMC article.
The chase for the RIG-I ligand--recent advances.
Schlee M, Hartmann G. Schlee M, et al. Among authors: hartmann g. Mol Ther. 2010 Jul;18(7):1254-62. doi: 10.1038/mt.2010.90. Epub 2010 May 11. Mol Ther. 2010. PMID: 20461060 Free PMC article. Review.
Activation of endothelial toll-like receptor 3 impairs endothelial function.
Zimmer S, Steinmetz M, Asdonk T, Motz I, Coch C, Hartmann E, Barchet W, Wassmann S, Hartmann G, Nickenig G. Zimmer S, et al. Among authors: hartmann g, hartmann e. Circ Res. 2011 May 27;108(11):1358-66. doi: 10.1161/CIRCRESAHA.111.243246. Epub 2011 Apr 14. Circ Res. 2011. PMID: 21493895
788 results