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Endothelial nitric oxide synthase in the microcirculation.
Shu X, Keller TC 4th, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE. Shu X, et al. Among authors: isakson be. Cell Mol Life Sci. 2015 Dec;72(23):4561-75. doi: 10.1007/s00018-015-2021-0. Epub 2015 Aug 25. Cell Mol Life Sci. 2015. PMID: 26390975 Free PMC article. Review.
Endothelial cell expression of haemoglobin α regulates nitric oxide signalling.
Straub AC, Lohman AW, Billaud M, Johnstone SR, Dwyer ST, Lee MY, Bortz PS, Best AK, Columbus L, Gaston B, Isakson BE. Straub AC, et al. Among authors: isakson be. Nature. 2012 Nov 15;491(7424):473-7. doi: 10.1038/nature11626. Epub 2012 Oct 31. Nature. 2012. PMID: 23123858 Free PMC article.
Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction.
Cechova S, Zeng Q, Billaud M, Mutchler S, Rudy CK, Straub AC, Chi L, Chan FR, Hu J, Griffiths R, Howell NL, Madsen K, Jensen BL, Palmer LA, Carey RM, Sung SS, Malakauskas SM, Isakson BE, Le TH. Cechova S, et al. Among authors: isakson be. Circulation. 2013 Oct 15;128(16):1770-80. doi: 10.1161/CIRCULATIONAHA.113.003301. Epub 2013 Sep 18. Circulation. 2013. PMID: 24048198
Hemoglobin α in the blood vessel wall.
Butcher JT, Johnson T, Beers J, Columbus L, Isakson BE. Butcher JT, et al. Among authors: isakson be. Free Radic Biol Med. 2014 Aug;73:136-42. doi: 10.1016/j.freeradbiomed.2014.04.019. Epub 2014 May 14. Free Radic Biol Med. 2014. PMID: 24832680 Free PMC article. Review.
Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction.
Straub AC, Butcher JT, Billaud M, Mutchler SM, Artamonov MV, Nguyen AT, Johnson T, Best AK, Miller MP, Palmer LA, Columbus L, Somlyo AV, Le TH, Isakson BE. Straub AC, et al. Among authors: isakson be. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2594-600. doi: 10.1161/ATVBAHA.114.303974. Epub 2014 Oct 2. Arterioscler Thromb Vasc Biol. 2014. PMID: 25278292 Free PMC article.
A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.
Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE. Billaud M, et al. Among authors: isakson be. Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824. Sci Signal. 2015. PMID: 25690012 Free PMC article.
Emerging concepts regarding pannexin 1 in the vasculature.
Good ME, Begandt D, DeLalio LJ, Keller AS, Billaud M, Isakson BE. Good ME, et al. Among authors: isakson be. Biochem Soc Trans. 2015 Jun;43(3):495-501. doi: 10.1042/BST20150045. Biochem Soc Trans. 2015. PMID: 26009197 Free PMC article. Review.
157 results