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Endothelial nitric oxide synthase in the microcirculation.
Shu X, Keller TC 4th, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE. Shu X, et al. Among authors: columbus l. Cell Mol Life Sci. 2015 Dec;72(23):4561-75. doi: 10.1007/s00018-015-2021-0. Epub 2015 Aug 25. Cell Mol Life Sci. 2015. PMID: 26390975 Free PMC article. Review.
Endothelial cell expression of haemoglobin α regulates nitric oxide signalling.
Straub AC, Lohman AW, Billaud M, Johnstone SR, Dwyer ST, Lee MY, Bortz PS, Best AK, Columbus L, Gaston B, Isakson BE. Straub AC, et al. Among authors: columbus l. Nature. 2012 Nov 15;491(7424):473-7. doi: 10.1038/nature11626. Epub 2012 Oct 31. Nature. 2012. PMID: 23123858 Free PMC article.
Hemoglobin α in the blood vessel wall.
Butcher JT, Johnson T, Beers J, Columbus L, Isakson BE. Butcher JT, et al. Among authors: columbus l. Free Radic Biol Med. 2014 Aug;73:136-42. doi: 10.1016/j.freeradbiomed.2014.04.019. Epub 2014 May 14. Free Radic Biol Med. 2014. PMID: 24832680 Free PMC article. Review.
Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction.
Straub AC, Butcher JT, Billaud M, Mutchler SM, Artamonov MV, Nguyen AT, Johnson T, Best AK, Miller MP, Palmer LA, Columbus L, Somlyo AV, Le TH, Isakson BE. Straub AC, et al. Among authors: columbus l. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2594-600. doi: 10.1161/ATVBAHA.114.303974. Epub 2014 Oct 2. Arterioscler Thromb Vasc Biol. 2014. PMID: 25278292 Free PMC article.
Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).
Keller TC 4th, Butcher JT, Broseghini-Filho GB, Marziano C, DeLalio LJ, Rogers S, Ning B, Martin JN, Chechova S, Cabot M, Shu X, Best AK, Good ME, Simão Padilha A, Purdy M, Yeager M, Peirce SM, Hu S, Doctor A, Barrett E, Le TH, Columbus L, Isakson BE. Keller TC 4th, et al. Among authors: columbus l. Hypertension. 2016 Dec;68(6):1494-1503. doi: 10.1161/HYPERTENSIONAHA.116.08171. Epub 2016 Oct 31. Hypertension. 2016. PMID: 27802421 Free PMC article.
Heterocellular Contact Can Dictate Arterial Function.
Shu X, Ruddiman CA, Keller TCS 4th, Keller AS, Yang Y, Good ME, Best AK, Columbus L, Isakson BE. Shu X, et al. Among authors: columbus l. Circ Res. 2019 May 10;124(10):1473-1481. doi: 10.1161/CIRCRESAHA.118.313926. Circ Res. 2019. PMID: 30900949 Free PMC article.
The role of globins in cardiovascular physiology.
Keller TCS 4th, Lechauve C, Keller AS, Brooks S, Weiss MJ, Columbus L, Ackerman H, Cortese-Krott MM, Isakson BE. Keller TCS 4th, et al. Among authors: columbus l. Physiol Rev. 2022 Apr 1;102(2):859-892. doi: 10.1152/physrev.00037.2020. Epub 2021 Sep 6. Physiol Rev. 2022. PMID: 34486392 Free PMC article. Review.
Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.
Wolpe AG, Luse MA, Baryiames C, Schug WJ, Wolpe JB, Johnstone SR, Dunaway LS, Juśkiewicz ZJ, Loeb SA, Askew Page HR, Chen YL, Sabapathy V, Pavelec CM, Wakefield B, Cifuentes-Pagano E, Artamonov MV, Somlyo AV, Straub AC, Sharma R, Beier F, Barrett EJ, Leitinger N, Pagano PJ, Sonkusare SK, Redemann S, Columbus L, Penuela S, Isakson BE. Wolpe AG, et al. Among authors: columbus l. Sci Signal. 2024 Jan 30;17(821):eadg2622. doi: 10.1126/scisignal.adg2622. Epub 2024 Jan 30. Sci Signal. 2024. PMID: 38289985
56 results