Wang B - Search Results

1

Characterization of a Radical Intermediate in Lipoyl Cofactor Biosynthesis.

Lanz ND, Rectenwald JM, Wang B, Kakar ES, Laremore TN, Booker SJ, Silakov A. Lanz ND, et al. Among authors: wang b. J Am Chem Soc. 2015 Oct 21;137(41):13216-9. doi: 10.1021/jacs.5b04387. Epub 2015 Oct 9. J Am Chem Soc. 2015. PMID: 26390103

2

Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical S-adenosylmethionine methylase TsrM requires an unmodified N1 amine.

Blaszczyk AJ, Wang B, Silakov A, Ho JV, Booker SJ. Blaszczyk AJ, et al. Among authors: wang b. J Biol Chem. 2017 Sep 15;292(37):15456-15467. doi: 10.1074/jbc.M117.778548. Epub 2017 Jul 26. J Biol Chem. 2017. PMID: 28747433 Free PMC article.

3

NosN, a Radical S-Adenosylmethionine Methylase, Catalyzes Both C1 Transfer and Formation of the Ester Linkage of the Side-Ring System during the Biosynthesis of Nosiheptide.

LaMattina JW, Wang B, Badding ED, Gadsby LK, Grove TL, Booker SJ. LaMattina JW, et al. Among authors: wang b. J Am Chem Soc. 2017 Dec 6;139(48):17438-17445. doi: 10.1021/jacs.7b08492. Epub 2017 Nov 21. J Am Chem Soc. 2017. PMID: 29039940 Free PMC article.

4

Enhanced Solubilization of Class B Radical S-Adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli.

Lanz ND, Blaszczyk AJ, McCarthy EL, Wang B, Wang RX, Jones BS, Booker SJ. Lanz ND, et al. Among authors: wang rx, wang b. Biochemistry. 2018 Mar 6;57(9):1475-1490. doi: 10.1021/acs.biochem.7b01205. Epub 2018 Feb 19. Biochemistry. 2018. PMID: 29298049 Free PMC article.

5

Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance.

Dunham NP, Chang WC, Mitchell AJ, Martinie RJ, Zhang B, Bergman JA, Rajakovich LJ, Wang B, Silakov A, Krebs C, Boal AK, Bollinger JM Jr. Dunham NP, et al. Among authors: wang b. J Am Chem Soc. 2018 Jun 13;140(23):7116-7126. doi: 10.1021/jacs.8b01933. Epub 2018 Jun 4. J Am Chem Soc. 2018. PMID: 29708749 Free PMC article.

6

Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase.

Wang B, Blaszczyk AJ, Knox HL, Zhou S, Blaesi EJ, Krebs C, Wang RX, Booker SJ. Wang B, et al. Among authors: wang rx. Biochemistry. 2018 Aug 21;57(33):4972-4984. doi: 10.1021/acs.biochem.8b00693. Epub 2018 Aug 9. Biochemistry. 2018. PMID: 30036047 Free PMC article.

7

Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide.

Wang B, LaMattina JW, Badding ED, Gadsby LK, Grove TL, Booker SJ. Wang B, et al. Methods Enzymol. 2018;606:241-268. doi: 10.1016/bs.mie.2018.06.005. Epub 2018 Jul 20. Methods Enzymol. 2018. PMID: 30097095 Free PMC article.

8

Capturing Intermediates in the Reaction Catalyzed by NosN, a Class C Radical S-Adenosylmethionine Methylase Involved in the Biosynthesis of the Nosiheptide Side-Ring System.

Wang B, LaMattina JW, Marshall SL, Booker SJ. Wang B, et al. J Am Chem Soc. 2019 Apr 10;141(14):5788-5797. doi: 10.1021/jacs.8b13157. Epub 2019 Apr 1. J Am Chem Soc. 2019. PMID: 30865439 Free PMC article.

9

Steric Enforcement of cis-Epoxide Formation in the Radical C-O-Coupling Reaction by Which (S)-2-Hydroxypropylphosphonate Epoxidase (HppE) Produces Fosfomycin.

Zhou S, Pan J, Davis KM, Schaperdoth I, Wang B, Boal AK, Krebs C, Bollinger JM Jr. Zhou S, et al. Among authors: wang b. J Am Chem Soc. 2019 Dec 26;141(51):20397-20406. doi: 10.1021/jacs.9b10974. Epub 2019 Dec 11. J Am Chem Soc. 2019. PMID: 31769979 Free PMC article.

10

Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.

Knox HL, Chen PY, Blaszczyk AJ, Mukherjee A, Grove TL, Schwalm EL, Wang B, Drennan CL, Booker SJ. Knox HL, et al. Among authors: wang b. Nat Chem Biol. 2021 Apr;17(4):485-491. doi: 10.1038/s41589-020-00717-y. Epub 2021 Jan 18. Nat Chem Biol. 2021. PMID: 33462497 Free PMC article.

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