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Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.
Peeters JG, Vervoort SJ, Tan SC, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Creyghton MP, Coffer PJ, Mokry M, van Loosdregt J. Peeters JG, et al. Among authors: nieuwenhuis ee. Cell Rep. 2015 Sep 29;12(12):1986-96. doi: 10.1016/j.celrep.2015.08.046. Epub 2015 Sep 17. Cell Rep. 2015. PMID: 26387944 Free article.
Autoimmune disease-associated gene expression is reduced by BET-inhibition.
Peeters JG, Vervoort SJ, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Mokry M, van Loosdregt J. Peeters JG, et al. Among authors: nieuwenhuis ee. Genom Data. 2015 Nov 7;7:14-7. doi: 10.1016/j.gdata.2015.11.004. eCollection 2016 Mar. Genom Data. 2015. PMID: 26981351 Free PMC article.
FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis.
van Boxtel R, Gomez-Puerto C, Mokry M, Eijkelenboom A, van der Vos KE, Nieuwenhuis EE, Burgering BM, Lam EW, Coffer PJ. van Boxtel R, et al. Among authors: nieuwenhuis ee. Cell Death Differ. 2013 Sep;20(9):1219-29. doi: 10.1038/cdd.2013.81. Epub 2013 Jul 5. Cell Death Differ. 2013. PMID: 23832113 Free PMC article.
Canonical Wnt signaling negatively modulates regulatory T cell function.
van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ. van Loosdregt J, et al. Among authors: nieuwenhuis ee. Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15. Immunity. 2013. PMID: 23954131 Free article.
Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis.
Vervoort SJ, de Jong OG, Roukens MG, Frederiks CL, Vermeulen JF, Lourenço AR, Bella L, Vidakovic AT, Sandoval JL, Moelans C, van Amersfoort M, Dallman MJ, Bruna A, Caldas C, Nieuwenhuis E, van der Wall E, Derksen P, van Diest P, Verhaar MC, Lam EW, Mokry M, Coffer PJ. Vervoort SJ, et al. Elife. 2018 Dec 3;7:e27706. doi: 10.7554/eLife.27706. Elife. 2018. PMID: 30507376 Free PMC article.
143 results